Akt compositions for enhancing survival of cells
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United States of America Patent
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May 6, 2008
Grant Date -
N/A
app pub date -
Sep 29, 1999
filing date -
Oct 2, 1998
priority date (Note) -
Expired
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Abstract
This invention relates to methods and compositions for the treatment of apoptotic cell-death. In particular the invention relates to Akt molecules and their use in inhibiting apoptotic cell-death in cardiomyocytes, skeletal myocytes and/or vascular endothelial cells. In view of these discoveries, Akt molecules can be used to inhibit apoptotic cell-death of any of the foregoing cells, and in particular, to treat conditions (e.g., myocardial infarction) that result in increased apoptotic cell-death of cardiomyocytes, skeletal myocytes and/or vascular endothelial cells.
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