Modulation of Aurora B expression
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United States of America Patent
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May 20, 2008
Grant Date -
Dec 1, 2005
app pub date -
May 24, 2005
filing date -
May 24, 2004
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Compounds, compositions and methods are provided for modulating the expression of Aurora B. The compositions comprise oligonucleotides, targeted to nucleic acid encoding Aurora B. Methods of using these compounds for modulation of Aurora B expression and for diagnosis and treatment of diseases and conditions associated with expression of Aurora B are provided. Also provided are methods of using these compounds to modulate the growth of cancer cells, including p53-deficient cancer cells.
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