Antibodies against carbonic anhydrase IX (CA IX) tumor antigen
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United States of America Patent
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May 27, 2008
Grant Date -
Jan 29, 2004
app pub date -
Dec 2, 2002
filing date -
Dec 3, 2001
priority date (Note) -
Expired
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Abstract
The present invention relates generally to the generation and characterization of anti-CA IX monoclonal antibodies. The invention further relates to the use of such anti-CA IX antibodies in the diagnosis and treatment of disorders associated with increased activity of CA IX, in particular, tumors such as colorectal cancer, renal cell carcinoma (RCC), cervical and other cancers of epithelial origin.
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