Use of penetration enhancers and barrier disruption methods to enhance the immune response of antigen and adjuvant
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United States of America Patent
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May 27, 2008
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Mar 3, 2004
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Nov 14, 1996
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Abstract
A transcutaneous immunization system where the topical application of an adjuvant and an antigen or nucleic acid encoding for an antigen, to intact skin induces a systemic or mucosol antibody response. The immune response so elicited can be enhanced by physical or chemical skin penetration enhancement.
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