Peptide nucleic acids with polyamide-containing backbones

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United States of America Patent

PATENT NO 7378485
APP PUB NO 20030180734A1
SERIAL NO

10154890

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Abstract

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A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berg, Rolf Henrik 2000 Fredericksberg, DK 21 1500
Buchardt, Ole 3500 V.ae butted.rlose, DK 32 1309
Egholm, Michael 2000 Frederiksberg, DK 64 3797
Nielsen, Peter Eigil 2980 Kokkedal, DK 18 1470

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