System and method for analyte measurement using AC phase angle measurements

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7390667
APP PUB NO 20040157337A1
SERIAL NO

10688312

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddressTotal Patents
ROCHE DIABETES CARE, INC.INDIANAPOLIS, IN, US1146
ROCHE OPERATIONS LTD.HAMILTON62

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beaty, Terry A Indianapolis, IN 28 1651
Burke, David W Carmel, IN 48 3467
Kuhn, Lance S Fishers, IN 20 2135
Svetnik, Vladimir Morristown, NJ 16 2328

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (7)
4413628 pH Monitor electrode electrolyte cartridge 42 1980
4431004 Implantable glucose sensor 792 1981
5312762 Method of measuring an analyte by measuring electrical resistance of a polymer film reacting with the analyte 151 1991
5376254 Potentiometric electrochemical device for qualitative and quantitative analysis 40 1993
6121050 Analyte detection systems 66 1997
6246330 Elimination-absorber monitoring system 270 1998
6176988 Membrane electrode for measuring the glucose concentration in fluids 54 1998
 
WALES ABERYSTWYTH, UNIVERSITY OF (1)
5569591 Analytical or monitoring apparatus and method 162 1994
 
ALUSUISSE LONZA GROUP, AG (1)
5500350 Binding assay device 114 1994
 
Solid State Farms, Inc. (2)
5508203 Apparatus and method for radio frequency spectroscopy using spectral analysis 239 1993
5792668 Radio frequency spectral analysis for in-vitro or in-vivo environments 222 1996
 
Calypte, Inc. (1)
5447837 Multi-immunoassay diagnostic system for antigens or antibodies or both 72 1989
 
INTERNATIONAL TECHNIDYNE CORPORATION (1)
5504011 Portable test apparatus and associated method of performing a blood coagulation test 102 1994
 
ENDRESS + HAUSER GMBH + CO. KG (1)
6389891 Method and apparatus for establishing and/or monitoring the filling level of a medium in a container 56 2000
 
MIT Development Corporation (1)
6201607 Blood fluid characteristics analysis instrument 57 1999
 
TERUMO KABUSHIKI KAISHA (1)
4927516 Enzyme sensor 559 1987
 
RELIA BIOTECHNOLOGIES (SHENZHEN) LTD. (1)
6136610 Method and apparatus for performing a lateral flow assay 124 1998
 
DUQUESNE UNIVERSITY OF THE HOLY GHOST (1)
5469846 Implantable non-enzymatic electrochemical glucose sensor 515 1994
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (2)
5965380 Subcutaneous glucose electrode 1032 1999
6121009 Electrochemical analyte measurement system 1014 1999
 
ELI LILLY AND COMPANY (1)
5786584 Vial and cartridge reading device providing audio feedback for a blood glucose monitoring system 263 1996
 
ELAN PHARMA INTERNATIONAL LIMITED (1)
5820622 Analyte-controlled liquid delivery device and analyte monitor 577 1996
 
HUGHES ELECTRONICS CORPORATION (1)
5018164 Excimer laser ablation method and apparatus for microcircuit fabrication 66 1989
 
Moorlodge Ventures Limited (1)
6660141 Electrochemical sensor 17 2001
 
TECHNICAL CHEMICALS & PRODUCTS (1)
6574425 Reflectometer 80 1998
 
ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (1)
6259937 Implantable substrate sensor 718 1998
 
SIMCAH PARTNERS, L.P. (1)
* 5232667 Temperature control for portable diagnostic system using a non-contact temperature probe 65 1992
 
ANIMAS TECHNOLOGIES, LLC (5)
6180416 Method and device for predicting physiological values 460 1998
6144869 Monitoring of physiological analytes 570 1999
6272364 Method and device for predicting physiological values 616 1999
6326160 Microprocessors for use in a device for predicting physiological values 524 1999
6594514 Device for monitoring of physiological analytes 282 2001
 
Evreka, Inc. (1)
4436094 Monitor for continuous in vivo measurement of glucose concentration 546 1982
 
E. HELLER & COMPANY (4)
6134461 Electrochemical analyte 1222 1998
6175752 Analyte monitoring device and methods of use 1600 1998
6484046 Electrochemical analyte sensor 1012 2000
6565509 Analyte monitoring device and methods of use 1131 2000
 
TALL OAK VENTURES (1)
6153069 Apparatus for amperometric Diagnostic analysis 434 1995
 
EG&G OCEAN PRODUCTS, INC. (1)
4652830 Analyzer for comparative measurements of bulk conductivity 48 1985
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (3)
4671288 Electrochemical cell sensor for continuous short-term use in tissues and blood 982 1985
4703756 Complete glucose monitoring system with an implantable, telemetered sensor module 1052 1986
5650061 Large amplitude sinusoidal voltammetry 61 1995
 
Health Hero Network, Inc. (1)
6168563 Remote health monitoring and maintenance system 869 1999
 
X-RITE, INCORPORATED (1)
5118183 Automated strip reader densitometer 69 1990
 
E. I. DU PONT DE NEMOURS AND COMPANY (1)
4832814 Electrofusion cell and method of making the same 76 1987
 
CASCADE ENGINEERING, INC. (1)
6206282 RF embedded identification device 193 1999
 
ACTIMED LABORATORIES, INC. (1)
5234813 Method and device for metering of fluid samples and detection of analytes therein 135 1991
 
THE CLEVELAND CLINIC FOUNDATION (1)
4897162 Pulse voltammetry 375 1988
 
NATIONAL SCIENCE COUNCIL (1)
6042714 Method and chemical sensor for determining concentrations of hydrogen peroxide and its precursor in a liquid 60 1997
 
UNIVERSITY OF WASHINGTON (1)
6277641 Methods for analyzing the presence and concentration of multiple analytes using a diffusion-based chemical sensor 73 1999
 
Phase Dynamics, Inc. (1)
* 5748002 RF probe for montoring composition of substances 49 1996
 
DELSYS PHARMACEUTICAL CORPORATION (1)
6287595 Biomedical assay device 72 2000
 
BRITISH TECHNOLOGY GROUP LIMITED (1)
5691633 Method of and apparatus for determining a property of a sample 46 1995
 
NEXGEN MICROSYSTEMS, INC. (1)
5572159 Voltage-controlled delay element with programmable delay 67 1994
 
PROVENANCE ASSET GROUP LLC (1)
6295506 Measurement apparatus 688 1998
 
KUMETRIX, INC. (1)
5801057 Microsampling device and method of construction 446 1996
 
PROVALIS DIAGNOSTICS LIMITED (1)
6300142 Device and apparatus for conducting an assay 85 2000
 
Abbott Laboratories (2)
6540891 Test strip 404 2001
6600997 Analyte test instrument having improved calibration and communication processes 197 2001
 
GB BIOSCIENCES CORPORATION (1)
5654178 Immunoassay for tetrachloroisophthalonitrile (chlorothalonil), its derivatives and breakdown products 40 1995
 
STAT MEDICAL DEVICES, INC. (1)
6156051 Lancet having adjustable penetration depth 366 1999
 
SENSOR DIAGNOSTICS, INC. (1)
4713347 Measurement of ligand/anti-ligand interactions using bulk conductance 221 1985
 
ICU MEDICAL, INC. (1)
* 5261411 Thermal drift correction while continuously monitoring cardiac output 81 1991
 
LighTouch Medical, Inc. (1)
6044285 Method for non-invasive measurement of an analyte 147 1998
 
Hybrivet Systems, Inc. (1)
5039618 Test swab cartridge type device and method for detecting lead and cadmium 61 1990
 
GEMALTO SA (1)
6206292 Surface-printable RFID-transponders 190 2000
 
METRIKA LABORATORIES, INC. (2)
5580794 Disposable electronic assay device 405 1995
5837546 Electronic assay device and method 405 1996
 
PHARMACONTROL CORPORATION (1)
4750496 Method and apparatus for measuring blood glucose concentration 422 1987
 
ABBOTT DIABETES CARE INC. (25)
6071391 Enzyme electrode structure 633 1997
6251260 Potentiometric sensors for analytic determination 436 1998
6281006 Electrochemical affinity assay 404 1998
6638716 Rapid amperometric verification of PCR amplification of DNA 80 1998
6294281 Biological fuel cell and method 326 1998
6143164 Small volume in vitro analyte sensor 1072 1998
6338790 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 702 1999
6299757 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 649 1999
6461496 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 884 1999
6616819 Small volume in vitro analyte sensor and methods 699 1999
6156173 Enzyme electrode structure 116 2000
6551494 Small volume in vitro analyte sensor 644 2000
6592745 Method of using a small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 618 2000
6618934 Method of manufacturing small volume in vitro analyte sensor 911 2000
6654625 Mass transport limited in vivo analyte sensor 882 2000
6591125 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 1034 2000
6579690 Blood analyte monitoring through subcutaneous measurement 1044 2000
6503381 Biosensor 516 2000
6329161 Subcutaneous glucose electrode 1081 2000
6605200 Polymeric transition metal complexes and uses thereof 627 2000
6605201 Transition metal complexes with bidentate ligand having an imidazole ring and sensor constructed therewith 628 2000
6607658 Integrated lancing and measurement device and analyte measuring methods 585 2000
6560471 Analyte monitoring device and methods of use 1064 2001
6623501 Reusable ceramic skin-piercing device 521 2001
6531239 Biological fuel cell and methods 78 2001
 
INVERNESS MEDICAL TECHNOLOGY, INC. (3)
5708247 Disposable glucose test strips, and methods and compositions for making same 686 1996
5951836 Disposable glucose test strip and method and compositions for making same 479 1998
6241862 Disposable test strips with integrated reagent/blood separation layer 474 1999
 
INVERNESS MEDICAL SWITZERLAND GMBH (1)
5141868 Device for use in chemical test procedures 694 1989
 
KYOTO DAIICHI KAGAKU CO., LTD. (3)
5720862 Sensor and production method of and measurement method using the same 418 1996
6377896 Method and apparatus for determination of a substance coexisting with another substance 56 1999
6349230 Blood measuring instrument 65 2000
 
KROHNE MESSTECHNIK GMBH (1)
6401532 Fill level gauge 43 2001
 
BOEHRINGER, A CORP. OF GERMANY (1)
4510383 Device for the optical identification of a coding on a diagnostic test strip 75 1982
 
PANASONIC HEALTHCARE CO., LTD. (1)
6599406 Concentration measuring apparatus, test strip for the concentration measuring apparatus, biosensor system and method for forming terminal on the test strip 172 2000
 
Seiko Instruments & Electronics Ltd. (1)
4789804 Analytical device and method utilizing a piezoelectric crystal biosensor 141 1986
 
Visionary Medical Products Corporation (3)
5728074 Pen-type injector with a microprocessor and blood characteristic monitor 345 1994
5593390 Medication delivery device with a microprocessor and characteristic monitor 570 1995
5925021 Medication delivery device with a microprocessor and characteristic monitor 853 1997
 
OSMETECH TECHNOLOGY INC. (1)
6013170 Detection of analytes using reorganization energy 140 1998
 
ROCHE DIABETES CARE, INC. (31)
4731726 Patient-operated glucose monitor and diabetes management system 1366 1986
4797256 Registration device for blood test strips 89 1987
5053199 Electronically readable information carrier 180 1989
5128015 Method and apparatus for amperometric diagnostic analysis 332 1989
4963814 Regulated bifurcated power supply 64 1989
4999582 Biosensor electrode excitation circuit 238 1989
4999632 Analog to digital conversion with noise reduction 89 1989
5243516 Biosensing instrument and method 174 1989
5232668 Test strip holding and reading mechanism for a meter 143 1991
5246858 Apparatus and method for analyzing a body fluid 79 1991
5108564 Method and apparatus for amperometric diagnostic analysis 532 1991
5371687 Glucose test data acquisition and management system 600 1992
5284770 Meter verification method and apparatus 44 1993
5385846 Biosensor and method for hematocrit determination 186 1993
5352351 Biosensing meter with fail/safe procedures to prevent erroneous indications 612 1993
5405511 Biosensing meter with ambient temperature estimation method and system 253 1993
5413690 Potentiometric biosensor and the method of its use 376 1993
5379214 Method for reading the concentration of a medically significant component of a biological fluid from a test strip 90 1993
5437999 Electrochemical sensor 749 1994
5594906 Zero power receive detector for serial data interface 211 1994
5438271 Biosensing meter which detects proper electrode engagement and distinguishes sample and check strips 405 1994
5762770 Electrochemical biosensor test strip 369 1995
6162639 Embossed test strip system 249 1998
6413395 Biosensor apparatus 55 1999
6627057 Microsphere containing sensor 53 1999
6413213 Subscription based monitoring system and method 67 2000
6645359 Biosensor 102 2000
6540890 Biosensor 70 2000
6447657 Biosensor 85 2000
6544474 Device for determination of an analyte in a body fluid using small sample sizes 65 2001
* 7018843 Instrument 77 2001
 
MILES INC. (4)
4938860 Electrode for electrochemical sensors 393 1985
4806311 Multizone analytical element having labeled reagent concentration zone 178 1985
4806312 Multizone analytical element having detectable signal concentrating zone 132 1985
5250439 Use of conductive sensors in diagnostic assays 447 1992
 
INVERNESS MEDICAL - BIOSTAR INC. (1)
5639671 Methods for optimizing of an optical assay device 98 1995
 
NOVO NORDISK A/S (1)
5269891 Method and apparatus for determination of a constituent in a fluid 500 1993
 
AMP Incorporated (1)
4648665 Electronic key assemblies 49 1985
 
TRIVIDIA HEALTH, INC. (5)
5296192 Diagnostic test strip 86 1992
6525330 Method of strip insertion detection 89 2001
6541266 Method for determining concentration of an analyte in a test strip 291 2001
6562625 Distinguishing test types through spectral analysis 78 2001
6743635 System and methods for blood glucose sensing 508 2002
 
QUEEN MARY & WESTFIELD COLLEGE (1)
6300123 Sensor employing impedance measurements 51 1999
 
BECTON, DICKINSON AND COMPANY (2)
4628193 Code reading operations supervisor 155 1980
4703017 Solid phase assay with visual readout 344 1984
 
DADE BEHRING INC. (1)
4517291 Biological detection process using polymer-coated electrodes 103 1983
 
NANOGEN, INC. (1)
5605662 Active programmable electronic devices for molecular biological analysis and diagnostics 800 1993
 
CYTYC CORPORATION (1)
6394952 Point of care diagnostic systems 169 1998
 
3M INNOVATIVE PROPERTIES COMPANY (2)
6203952 Imaged article on polymeric substrate 119 1999
6399258 Method for patterning thin films 53 2001
 
AFFYMETRIX, INC. (1)
5922591 Integrated nucleic acid diagnostic device 701 1996
 
TECAN TRADING AG (1)
6143247 Affinity binding-based system for detecting particulates in a fluid 228 1997
 
PACKARD INSTRUMENT COMPANY, INC. (1)
6538735 Method and apparatus for producing and measuring light and for determining the amounts of analytes in microplate wells 45 2000
 
CONMED CORPORATION (1)
5921925 Biomedical electrode having a disposable electrode and a reusable leadwire adapter that interfaces with a standard leadwire connector 103 1997
 
HOUSTON ADVANCED RESEARCH CENTER (1)
5532128 Multi-site detection apparatus 227 1994
 
NIPRO DIAGNOSTICS, INC. (1)
6284550 Diagnostic sanitary test strip 83 1999
 
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (1)
5611900 Microbiosensor used in-situ 414 1995
 
LIFECAN, INC. (1)
6420128 Test strips for detecting the presence of a reduced cofactor in a sample and method for using the same 161 2000
 
ELECTROSYNTHESIS COMPANY (1)
5437772 Portable lead detector 71 1993
 
DERMAL DEVICES INC. (1)
5890489 Method for non-invasive determination of glucose in body fluids 85 1996
 
DR. HOLGER KIESEWETTER (1)
4547735 Instrument for measuring the hematocrit value of blood 68 1983
 
INVERNESS MEDICAL TECHNOLOGY (1)
5989917 Glucose monitor and test strip containers for use in same 152 1996
 
BOEHRINGER MANNHEIM GMBH (19)
4477575 Process and composition for separating plasma or serum from whole blood 284 1981
4476149 Process for the production of an analysis test strip 97 1982
4592893 Analysis test strip 110 1984
4578716 Method of and apparatus for making a test strip and a test strip made by such method 61 1984
4676653 Apparatus for determining the diffuse reflectivity of a sample surface of small dimensions 86 1984
4816224 Device for separating plasma or serum from whole blood and analyzing the same 161 1987
4834234 Container for test strips 98 1988
5035862 Analytical system for the determination of a component of a fluid 53 1988
5413764 Test carrier analysis system 62 1990
5143694 Test strip evaluating instrument for multiple test strips 73 1990
5122244 Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor 239 1991
5281395 Test carrier analysis system 233 1991
5286362 Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor 509 1993
5424035 Test strip analysis system 155 1994
5489414 System for analyzing compounds contained in liquid samples 276 1994
5556789 Device for the simultaneous determination of several analytes 56 1994
5445967 Method for analyzing a component of a liquid sample 71 1994
5645798 Test elements in sealed chambers for analyzing compounds contained in liquid samples 101 1995
5757666 System for analyzing compounds contained liquid samples 103 1996
 
LONZA GROUP AG (1)
5604110 Binding assay device 64 1995
 
MEDISENSE, INC. (7)
4545382 Sensor for components of a liquid mixture 808 1982
4711245 Sensor for components of a liquid mixture 731 1984
5509410 Strip electrode including screen printing of a single layer 784 1994
5682884 Strip electrode with screen printing 534 1994
5727548 Strip electrode with screen printing 470 1995
5628890 Electrochemical sensor 998 1995
5849174 Electrodes and their use in analysis 230 1997
 
OttoSensors Corporation (1)
4682602 Probe for medical application 319 1985
 
LRE Technology Partner GmbH (3)
5904898 Test strip 78 1998
6315951 Test strip measuring system 57 1999
6525549 Method for determining the concentration of a substance in a liquid by measuring electrical current in a test strip 61 2000
 
PANASONIC CORPORATION (1)
5264103 Biosensor and a method for measuring a concentration of a substrate in a sample 684 1992
 
QUESTSTAR MEDICAL, INC. (1)
5279294 Medical diagnostic system 873 1990
 
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (1)
5670031 Electrochemical sensor 369 1995
 
FA. LPKF CAD/CAM SYSTEME GMBH (1)
5576073 Method for patterned metallization of a substrate surface 70 1995
 
ACUSON CORPORATION (1)
6300961 Ultrasonic system and method for processing data 42 1999
 
SMITHKLINE DIAGNOSTICS, INC. (1)
4935106 Ion selective/enzymatic electrode medical analyzer device and method of use 54 1985
 
EURUS LLC (1)
5019974 Diabetes management system and apparatus 913 1990
 
HITACHI, LTD. (1)
5470533 Test strip supply apparatus and analyzer using same 53 1993
 
UMM Electronics, Inc. (1)
6150124 Method for passively determining the application of a sample fluid on an analyte strip 54 1999
 
LPKF LASER & ELECTRONICS AG (1)
5593739 Method of patterned metallization of substrate surfaces 60 1996
 
CUMMINS FILTRATION INC. (1)
2004/0094,459 LIQUID FILTER WITH SEPARATE AND CALIBRATED VAPOR RELEASE 2 2003
 
DISETRONIC LICENSING AG (2)
5411647 Techniques to improve the performance of electrochemical sensors 952 1994
5695623 Glucose measuring device 645 1994
 
MARCONI COMMUNICATIONS LIMITED (1)
6576461 Electrochemical affinity assay 69 2001
 
I-STAT CORPORATION (3)
5096669 Disposable sensing device for real time fluid analysis 551 1988
4954087 Static-free interrogating connector for electric components 86 1990
5112455 Method for analytically utilizing microfabricated sensors during wet-up 229 1990
 
CLINICAL DIAGNOSTIC SYSTEMS INC. (4)
4323536 Multi-analyte test device 145 1980
4413407 Method for forming an electrode-containing device with capillary transport between electrodes 87 1981
4552458 Compact reflectometer 122 1983
5126952 Bar coding calibration 40 1991
 
FIRST NATIONAL BANK OF BOSTON, THE (2)
4686479 Apparatus and control kit for analyzing blood sample values including hematocrit 96 1985
4759828 Glucose electrode and method of determining glucose 579 1987
 
Optikos Corporation (1)
6226081 Optical height of fill detection system and associated methods 61 1998
 
MAGELLAN DIAGNOSTICS, INC. (1)
6391558 Electrochemical detection of nucleic acid sequences 111 2000
 
CIBA CORNING DIAGNOSTICS CORP. (2)
5066372 Unitary multiple electrode sensor 92 1990
5421189 Electrical connection system for electrochemical sensors 55 1994
 
CORANGE INTERNATIONAL LIMITED (UNDIVIDED 1/2 INTEREST) (1)
5366609 Biosensing meter with pluggable memory key 526 1993
 
Hygeia Sciences, Inc. (1)
5141850 Porous strip form assay device method 225 1990
 
ASULAB S.A. (1)
5395504 Electrochemical measuring system with multizone sensors 475 1994
 
SIEMENS AKTIENGESELLSCHAFT (2)
4477314 Method for determining sugar concentration 428 1983
4919770 Method for determining the concentration of electro-chemically convertible substances 173 1986
 
ABBOTT LABORATORIES (9)
5075077 Test card for performing assays 194 1988
5311426 Apparatus and method for providing assay calibration data 95 1992
5635364 Assay verification control for an automated analytical system 100 1994
5820551 Strip electrode with screen printing 574 1995
6129823 Low volume electrochemical sensor 347 1997
6087182 Reagentless analysis of biological samples 104 1998
6565738 Diagnostic test for the measurement of analyte in abiological fluid 95 1999
6377894 Analyte test instrument having improved calibration and communication processes 323 1999
6526298 Method for the non-invasive determination of analytes in a selected volume of tissue 353 2000
 
INSTITUT FUR CHEMO-UND BIOSENSORIK MUNSTER E.V. (1)
* 6004442 Analyte-selective sensor 90 1997
 
GENZYME CORPORATION (1)
5656502 Test strip holder and method of use 105 1995
 
PBI TECHNOLOGY, INC. (1)
6102872 Glucose detector and method 91 1998
 
LIFESCAN, IC., A CORP. OF CA. (1)
4976724 Lancet ejector mechanism 323 1989
 
Microcor, Inc. (2)
5526808 Method and apparatus for noninvasively determining hematocrit 94 1995
5642734 Method and apparatus for noninvasively determining hematocrit 119 1996
 
CAMBRIDGE LIFE SCIENCES PLC (2)
4970145 Immobilized enzyme electrodes 450 1988
5846744 Sensors based on polymer transformation 268 1996
 
Biologix, Inc. (2)
4940945 Interface circuit for use in a portable blood chemistry measuring apparatus 75 1987
* 4929426 Portable blood chemistry measuring apparatus 174 1988
 
FUJI ELECTRIC CO., LTD. (1)
4407959 Blood sugar analyzing apparatus 273 1981
 
BAYER HEALTHCARE LLC (2)
5630986 Dispensing instrument for fluid monitoring sensors 377 1995
5653863 Method for reducing bias in amperometric sensors 617 1996
 
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (2)
4805624 Low-potential electrochemical redox sensors 426 1987
6271044 Method and kit for detecting an analyte 51 1998
 
DRAGERWERK AKTIENGESELLSCHAFT (1)
4499423 Circuit arrangement for correction of a sensor output 43 1981
 
ASSURANCE BIOTECH LLC (1)
6514769 Multiple analyte assay device with sample integrity monitoring system 82 1999
 
Bayer Aktiengesellschaft (1)
5916156 Electrochemical sensors having improved selectivity and enhanced sensitivity 209 1997
 
SHIMADZU CORPORATION (1)
4820399 Enzyme electrodes 500 1985
 
Cardiac Pacemakers, Inc. (1)
4679562 Glucose sensor 352 1986
 
University Patents, Inc. (1)
4440175 Membrane electrode for non-ionic species 309 1981
 
TECHNIMED CORPORATION (1)
4877580 Assay kit including an analyte test strip and a color comparator 90 1988
 
Migrata U.K. Ltd. (1)
4654197 Cuvette for sampling and analysis 422 1984
 
NIPPON TELEGRAPH AND TELEPHONE CORPORATION (1)
5389215 Electrochemical detection method and apparatus therefor 94 1993
 
LXN CORPORATION (1)
5885839 Methods of determining initiation and variable end points for measuring a chemical reaction 65 1997
 
BAYER CORPORATION (9)
5552116 Test strip pick-up mechanism in automated analyzer 49 1995
5620579 Apparatus for reduction of bias in amperometric sensors 305 1995
5665215 Method and apparatus for making predetermined events with a biosensor 98 1995
5723284 Control solution and method for testing the performance of an electrochemical device for determining the concentration of an analyte in blood 240 1996
5883378 Apparatus and methods for transmitting electrical signals indicative of optical interactions between a light beam and a flowing suspension of particles 95 1996
5856195 Method and apparatus for calibrating a sensor element 231 1996
5798031 Electrochemical biosensor 400 1997
6391645 Method and apparatus for correcting ambient temperature effect in biosensors 92 1997
6246966 Method and apparatus for data management authentication in a clinical analyzer 62 1998
 
IMPERIAL CHEMICAL INDUSTRIES PLC (1)
4935105 Methods of operating enzyme electrode sensors 343 1989
 
GENETICS INTERNATIONAL, INC. (1)
4820636 Electrochemical assay for cis-diols 74 1986
 
PANASONIC HEALTHCARE HOLDINGS CO., LTD. (11)
5582697 Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same 700 1995
5575895 Biosensor and method for producing the same 474 1995
5650062 Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same 481 1995
6004441 Biosensor 349 1997
6225078 Method for quantitative measurement of a substrate 195 1998
6258254 Biosensor 196 1998
6656702 Biosensor containing glucose dehydrogenase 209 1999
RE36991 Biosensor and method for producing the same 218 1999
6309526 Biosensor 230 1999
6340428 Device and method for determining the concentration of a substrate 79 1999
6342364 Cholesterol sensor and method of determining cholesterol 48 2001
 
BECKMAN COULTER, INC. (3)
5344754 Assay timed by electrical resistance change and test strip 85 1993
5554531 Device for performing timed assay by electrical resistance change 81 1995
6061128 Verification device for optical clinical assay systems 192 1998
 
RUBICON INVESTMENTS, INC. (1)
6128519 System and method for measuring a bioanalyte such as lactate 94 1998
 
THERASENSE, INC. (5)
6103033 Process for producing an electrochemical biosensor 1195 1998
6120676 Method of using a small volume in vitro analyte sensor 1192 1999
6576101 Small volume in vitro analyte sensor 659 1999
6162611 Subcutaneous glucose electrode 1023 2000
6514718 Subcutaneous glucose electrode 853 2001
 
ALZA CORPORATION (1)
6091975 Minimally invasive detecting device 836 1998
 
ORASURE TECHNOLOGIES, INC. (1)
5112758 Treating body fluids for diagnostic testing 50 1988
 
Sensors for Medicine and Science, Inc. (1)
6330464 Optical-based sensing devices 539 1999
 
ESA BIOSCIENCES, INC. (1)
5873990 Handheld electromonitor device 206 1996
 
Spectrum Systems, Inc. (1)
5508200 Method and apparatus for conducting multiple chemical assays 264 1992
 
ARKRAY, INC. (2)
6180062 Device for analyzing a sample 60 1999
6576117 Method and apparatus for electrochemical measurement using statistical technique 411 2001
 
Thomson-CSF (1)
4420564 Blood sugar analyzer having fixed enzyme membrane sensor 415 1981
 
CALIFORNIA INSTITUTE OF TECHNOLOGY (3)
5788833 Sensors for detecting analytes in fluids 125 1996
5911872 Sensors for detecting analytes in fluids 121 1997
6170318 Methods of use for sensor based fluid detection devices 248 1998
 
MEDTRONIC CRYOCATH LP (1)
5232516 Thermoelectric device with recuperative heat exchangers 180 1991
 
SIEMENS MEDICAL SOLUTIONS USA, INC. (2)
5971923 Ultrasound system and method for interfacing with peripherals 90 1997
6262749 Ultrasonic system and method for data transfer, storage and/or processing 62 1997
 
HYPOGUARD LIMITED (1)
5494638 Support membrane 61 1994
 
AT&T Bell Laboratories (1)
5353351 Secure teleconferencing 81 1992
 
JPMORGAN CHASE BANK, N.A. (1)
5597532 Apparatus for determining substances contained in a body fluid 159 1994
 
RIGAKU CORPORATION (1)
6570390 Method for measuring surface leakage current of sample 37 2001
 
Mallinckrodt Sensor Systems, Inc. (1)
4734184 Self-activating hydratable solid-state electrode apparatus 135 1987
 
Hosiden Electronics Co., Ltd. (1)
4810203 Electrical connector 60 1987
 
NOVA BIOMEDICAL CORPORATION (3)
4975647 Controlling machine operation with respect to consumable accessory units 210 1988
6258229 Disposable sub-microliter volume sensor and method of making 301 1999
6287451 Disposable sensor and method of making 194 1999
 
SYVA COMPANY (1)
5439826 Method of distinguishing among strips for different assays in an automated instrument 71 1988
 
ROCHE OPERATIONS LTD. (3)
5997817 Electrochemical biosensor test strip 502 1997
6270637 Electrochemical biosensor test strip 327 1999
6645368 Meter and method of using the meter for determining the concentration of a component of a fluid 283 2000
 
ROCHE DIAGNOSTICS CORPORATION (3)
4642295 Methods of determining fructosamine levels in blood samples 59 1982
5288636 Enzyme electrode system 593 1990
5508171 Assay method with enzyme electrode system 544 1994
 
GENERAL ELECTRIC COMPANY (1)
4865873 Electroless deposition employing laser-patterned masking layer 85 1987
 
MOLECULAR DEVICES CORPORATION (2)
4849330 Photoresponsive redox detection and discrimination 84 1985
4956275 Migratory detection immunoassay 116 1987
 
Miles Laboratories, Inc. (1)
4714874 Test strip identification and instrument calibration 212 1985
 
The BOC Group, Inc. (1)
4407290 Blood constituent measuring device and method 322 1981
 
ROCHE DIAGNOSTICS OPERATIONS, INC. (4)
5526111 Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control 55 1993
5686659 Fluid dose flow and coagulation sensor for medical instrument 68 1995
5710622 Fluid dose, flow and coagulation sensor for medical instrument 40 1995
5832921 Analog heater control for medical instrument 45 1995
 
ST. JUDE MEDICAL, INC. (1)
4795542 Electrochemical concentration detector device 159 1986
 
RHEONIX, INC. (1)
6358752 Liposome-enhanced test device and method 67 1999
 
Ortho Pharmaceutical Corporation (1)
5179288 Apparatus and method for measuring a bodily constituent 70 1991
 
SEGARS CALIFORNIA PARTNERS, LP (1)
5220920 Electrochemical measurement system having interference reduction circuit 88 1991
 
MicroFab Technologies, Inc. (1)
5658802 Method and apparatus for making miniaturized diagnostic arrays 235 1995
 
APEX BIOTECHNOLOGY CORP. (1)
6491803 Test strip and biosensor incorporating with nanometer metal particles 79 2001
 
Innovative Biotechnologies, Inc. (1)
6159745 Interdigitated electrode arrays for liposome-enhanced immunoassay and test device 56 1999
 
WAVESENSE, INC. (1)
6136549 systems and methods for performing magnetic chromatography assays 109 1999
 
SIEMENS HEALTHCARE DIAGNOSTICS INC. (7)
5477326 Spectrophotometer arrangement with multi-detector readhead 66 1994
5569608 Quantitative detection of analytes on immunochromatographic strips 154 1995
5691486 Apparatus and methods for selecting a variable number of test sample aliquots to mix with respective reagents 64 1996
5719667 Apparatus for filtering a laser beam in an analytical instrument 93 1996
5745308 Methods and apparatus for an optical illuminator assembly and its alignment 105 1996
5945341 System for the optical identification of coding on a diagnostic test strip 105 1996
6316264 Test strip for the assay of an analyte in a liquid sample 65 1999
 
Silver Lake Corporation (1)
6287875 Internally referenced competitive assays 50 2000
 
Keith & Rumph Inventors, Inc. (1)
6126609 Apparatus for taking blood samples from a patient 35 1998
 
LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (1)
5698083 Chemiresistor urea sensor 130 1995
 
CASE WESTERN RESERVE UNIVERSITY (1)
4571292 Apparatus for electrochemical measurements 539 1982
 
OPTISCAN, INC. (1)
5515847 Self-emission noninvasive infrared spectrophotometer 199 1994
 
QBC DIAGNOSTICS, INC. (4)
5635362 Assay of blood or other biologic samples for target analytes 72 1994
5834217 Assay of blood or other biologic samples for target analytes 74 1996
5759794 Assay of blood or other biologic samples for target analytes 53 1996
5776710 Assay of blood or other biologic samples for target analytes 72 1996
 
LIFESCAN, INC. (62)
4935346 Minimum procedure system for the determination of analytes 318 1986
5049487 Automated initiation of timing of reflectance readings 530 1988
5059394 Analytical device for the automated determination of analytes in fluids 417 1988
5179005 Minimum procedure system for the determination of analytes 282 1988
5306623 Visual blood glucose concentration test strip 287 1991
5187100 Dispersion to limit penetration of aqueous solutions into a membrane 222 1991
5418142 Glucose test strip for whole blood 253 1992
5304468 Reagent test strip and apparatus for determination of blood glucose 737 1993
5426032 No-wipe whole blood glucose test strip 359 1993
5453360 Oxidative coupling dye for spectrophotometric quantitive analysis of analytes 185 1994
5515170 Analyte detection device having a serpentine passageway for indicator strips 211 1994
5526120 Test strip with an asymmetrical end insuring correct insertion for measuring 452 1994
5563031 Highly stable oxidative coupling dye for spectrophotometric determination of analytes 194 1994
6335203 Optically readable strip for analyte detection having on-strip orientation index 182 1994
5563042 Whole blood glucose test strip 275 1995
6395227 Test strip for measuring analyte concentration over a broad range of sample volume 161 1995
5620863 Blood glucose strip having reduced side reactions 197 1995
5922530 Stable coupling dye for photometric determination of analytes 153 1995
5605837 Control solution for a blood glucose monitor 212 1996
5780304 Method and apparatus for analyte detection having on-strip standard 223 1996
5843691 Visually-readable reagent test strip 216 1996
6168957 Diagnostic test strip having on-strip calibration 217 1997
5789255 Blood glucose strip having reduced sensitivity to hematocrit 191 1997
5843692 Automatic initiation of a time interval for measuring glucose concentration in a sample of whole blood 233 1997
5968760 Temperature-Independent Blood Glucose Measurement 191 1997
6284125 Electrochemical cell 251 1998
6045567 Lancing device causing reduced pain 270 1999
6197040 Lancing device having a releasable connector 231 1999
6179979 Electrochemical cell 175 1999
6200773 Diagnostics based on tetrazolium compounds 172 1999
6174420 Electrochemical cell 154 1999
6268162 Reflectance measurement of analyte concentration with automatic initiation of timing 240 1999
6193873 Sample detection to initiate timing of an electrochemical assay 415 1999
6521182 Fluidic device for medical diagnostics 198 1999
6261519 Medical diagnostic device with enough-sample indicator 211 1999
6379513 Sensor connection means 81 1999
6454921 Electrochemical cell 54 1999
6218571 8-(anilino)-1-naphthalenesulfonate analogs 143 1999
6475372 Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations 327 2000
6485923 Reagent test strip for analyte determination having hemolyzing agent 163 2000
6325917 Method and apparatus for automatic analysis 47 2000
6571651 Method of preventing short sampling of a capillary or wicking fill device 198 2000
6488827 Capillary flow control in a medical diagnostic device 176 2000
6592744 Method of filling an amperometric cell 143 2000
6444115 Electrochemical method for measuring chemical reaction rates 227 2000
6632349 Hemoglobin sensor 239 2000
6638415 Antioxidant sensor 174 2000
6413410 Electrochemical cell 277 2000
6475360 Heated electrochemical cell 218 2000
6555061 Multi-layer reagent test strip 225 2000
6521110 Electrochemical cell 246 2000
6531322 Visual blood glucose test strip 167 2000
6558528 Electrochemical test strip cards that include an integral dessicant 215 2000
6512986 Method for automated exception-based quality control compliance for point-of-care devices 151 2000
6489133 Apparatus for determinating the concentration of glucose in whole blood 163 2001
6549796 Monitoring analyte concentration using minimally invasive devices 445 2001
6501976 Percutaneous biological fluid sampling and analyte measurement devices and methods 216 2001
6576416 Analyte measurement device and method of use 196 2001
6491870 Optically readable strip for analyte detection having on-strip orientation index 157 2001
6689411 Solution striping system 172 2001
6676995 Solution striping system 198 2002
6572822 Visual blood glucose test strip 162 2002
 
MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (6)
4897173 Biosensor and method for making the same 542 1987
5120420 Biosensor and a process for preparation thereof 785 1989
5266179 Quantitative analysis method and its system using a disposable sensor 835 1991
5192415 Biosensor utilizing enzyme and a method for producing the same 489 1992
5658443 Biosensor and method for producing the same 166 1994
5948289 Laser beam machining method 55 1996
 
MATRIA HEALTHCARE, LLC (1)
5182707 Apparatus for recording reagent test strip data by comparison to color lights on a reference panel 288 1990
 
YASSINZADEH, ZIA (1)
5700695 Sample collection and manipulation method 401 1994
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
FÉINICS AMATECH TEORANTA (1)
9575027 Systems and methods of discriminating between a control sample and a test fluid using capacitance 0 2013
 
ASCENSIA DIABETES CARE HOLDINGS AG (8)
8401873 Health data management device 1 2008
8649997 Systems and methods for predicting ambient temperature in a fluid analyte meter 3 2009
* 2011/0191,059 Systems and Methods for Predicting Ambient Temperature in a Fluid Analyte Meter 28 2009
8617381 System and apparatus for determining temperatures in a fluid analyte system 8 2010
* 2010/0319,436 System and Apparatus for Determining Temperatures in a Fluid Analyte System 19 2010
9189598 Fluid analyte meter 0 2013
9097650 System and apparatus for determining temperatures in a fluid analyte system 1 2013
9664644 System and apparatus for determining temperatures in a fluid analyte system 0 2015
 
Other [Check patent profile for assignment information] (1)
9927388 Systems, devices, and methods for measuring whole blood hematocrit based on initial fill velocity 0 2014
 
ROCHE DIABETES CARE, INC. (4)
* 2007/0264,721 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT USING A NONLINEAR SAMPLE RESPONSE 115 2007
8148164 System and method for determining the concentration of an analyte in a sample fluid 4 2009
8298828 System and method for determining the concentration of an analyte in a sample fluid 2 2012
8586373 System and method for determining the concentration of an analyte in a sample fluid 0 2012
 
CILAG GMBH INTERNATIONAL (6)
8551320 System and method for measuring an analyte in a sample 6 2009
8932445 Systems and methods for improved stability of electrochemical sensors 0 2010
8617370 Systems and methods of discriminating between a control sample and a test fluid using capacitance 1 2010
9784707 System and method for measuring an analyte in a sample 0 2012
9575026 Systems and methods of discriminating between a control sample and a test fluid using capacitance 0 2013
9347910 Systems and methods for improved stability of electrochemical sensors 0 2015
 
LIFESCAN SCOTLAND LIMITED (5)
9903830 Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte 0 2012
9903831 Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte and derived biosensor parameters 0 2012
9638656 Accurate analyte measurements for electrochemical test strip based on multiple discrete measurements defined by sensed physical characteristic(s) of the sample containing the analyte 0 2012
9459231 Method and system to determine erroneous measurement signals during a test measurement sequence 0 2013
9243276 Method and system to determine hematocrit-insensitive glucose values in a fluid sample 9 2013
 
DEXCOM, INC. (7)
9848809 Advanced analyte sensor calibration and error detection 0 2012
9801575 Advanced analyte sensor calibration and error detection 0 2012
9149220 Advanced analyte sensor calibration and error detection 4 2012
9451908 Analyte sensor 1 2012
9700253 Systems and methods for processing analyte sensor data 0 2013
9433376 Systems and methods for processing analyte sensor data 0 2013
9808190 Advanced analyte sensor calibration and error detection 0 2013
 
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (1)
9903832 Methods for measuring analyte concentration 0 2015
 
ROCHE OPERATIONS LTD. (5)
* 7981363 System and method for analyte measurement 14 2008
* 2008/0098,802 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT 126 2008
* 2011/0236,963 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT 0 2011
* 8691152 System and method for analyte measurement 0 2012
* 2012/0135,508 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT 17 2012
 
LIFESCAN, INC. (20)
8529751 Systems and methods for discriminating control solution from a physiological sample 0 2006
* 2007/0235,347 Systems and Methods for Discriminating Control Solution from a Physiological Sample 135 2006
8778168 Systems and methods of discriminating control solution from a physiological sample 2 2008
* 2009/0084,687 SYSTEMS AND METHODS OF DISCRIMINATING CONTROL SOLUTION FROM A PHYSIOLOGICAL SAMPLE 140 2008
8603768 System and method for measuring an analyte in a sample 0 2009
8486649 System and method for measuring an analyte in a sample 0 2009
8877034 Systems, devices, and methods for measuring whole blood hematocrit based on initial fill velocity 1 2009
8101065 Systems, devices, and methods for improving accuracy of biosensors using fill time 9 2009
* 2011/0155,585 Systems, Devices, and Methods for Improving Accuracy of Biosensors Using Fill Time 13 2009
* 2011/0155,584 Systems, Devices, and Methods for Measuring Whole Blood Hematocrit Based on Initial Fill Velocity 9 2009
8449740 Systems and methods for discriminating control solution from a physiological sample 0 2010
* 2011/0011,752 SYSTEMS AND METHODS FOR DISCRIMINATING CONTORL SOLUTION FROM A PHYSIOLOGICAL SAMPLE 15 2010
8623198 Systems, devices, and methods for improving accuracy of biosensors using fill time 3 2010
9157110 Systems and methods of discriminating control solution from a physiological sample 0 2012
9739745 System and method for measuring an analyte in a sample 0 2012
8916040 System and method for measuring an analyte in a sample 0 2012
8709739 System and method for measuring an analyte in a sample 1 2012
9274078 Systems and methods of discriminating control solution from a physiological sample 0 2013
9404888 Systems, devices and methods for improving accuracy of biosensors using fill time 0 2013
9739749 System and method for measuring an analyte in a sample 0 2014
* Cited By Examiner

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
11.5 Year Payment $7400.00 $3700.00 $1850.00 Dec 24, 2019
Fee Large entity fee small entity fee micro entity fee
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00