US Patent No: 7,390,667

Number of patents in Portfolio can not be more than 2000

System and method for analyte measurement using AC phase angle measurements

ALSO PUBLISHED AS: 20040157337
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Abstract

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A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ROCHE DIABETES CARE, INC.INDIANAPOLIS, IN, US811
ROCHE OPERATIONS LTD.HAMILTON60

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beaty, Terry A Indianapolis, IN 28 727
Burke, David W Carmel, IN 48 1498
Kuhn, Lance S Fishers, IN 20 945
Svetnik, Vladimir Morristown, NJ 16 1318

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (7)
4,413,628 pH Monitor electrode electrolyte cartridge 38 1980
4,431,004 Implantable glucose sensor 641 1981
5,312,762 Method of measuring an analyte by measuring electrical resistance of a polymer film reacting with the analyte 141 1991
5,376,254 Potentiometric electrochemical device for qualitative and quantitative analysis 35 1993
6,121,050 Analyte detection systems 59 1997
6,246,330 Elimination-absorber monitoring system 215 1998
6,176,988 Membrane electrode for measuring the glucose concentration in fluids 48 1998
 
UNIVERSITY COLLEGE OF WALES, ABERYSTWYTH, THE (1)
5,569,591 Analytical or monitoring apparatus and method 147 1994
 
ALUSUISSE LONZA GROUP, AG (1)
5,500,350 Binding assay device 99 1994
 
Solid State Farms, Inc. (2)
5,508,203 Apparatus and method for radio frequency spectroscopy using spectral analysis 193 1993
5,792,668 Radio frequency spectral analysis for in-vitro or in-vivo environments 200 1996
 
Calypte, Inc. (1)
5,447,837 Multi-immunoassay diagnostic system for antigens or antibodies or both 66 1989
 
International Technidyne Corporation (1)
5,504,011 Portable test apparatus and associated method of performing a blood coagulation test 81 1994
 
ENDRESS + HAUSER GMBH + CO. KG (1)
6,389,891 Method and apparatus for establishing and/or monitoring the filling level of a medium in a container 49 2000
 
MIT DEVELOPMENT CORPORATION (1)
6,201,607 Blood fluid characteristics analysis instrument 52 1999
 
TERUMO KABUSHIKI KAISHA (1)
4,927,516 Enzyme sensor 451 1987
 
DUQUESNE UNIVERSITY OF THE HOLY GHOST (1)
5,469,846 Implantable non-enzymatic electrochemical glucose sensor 409 1994
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (2)
5,965,380 Subcutaneous glucose electrode 753 1999
6,121,009 Electrochemical analyte measurement system 714 1999
 
Eli Lilly and Company (1)
5,786,584 Vial and cartridge reading device providing audio feedback for a blood glucose monitoring system 222 1996
 
ELAN PHARMA INTERNATIONAL LIMITED (1)
5,820,622 Analyte-controlled liquid delivery device and analyte monitor 430 1996
 
HUGHES ELECTRONICS CORPORATION (1)
5,018,164 Excimer laser ablation method and apparatus for microcircuit fabrication 61 1989
 
TECHNICAL CHEMICALS & PRODUCTS (1)
6,574,425 Reflectometer 59 1998
 
ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (1)
6,259,937 Implantable substrate sensor 543 1998
 
ANIMAS TECHNOLOGIES LLC (5)
6,180,416 Method and device for predicting physiological values 377 1998
6,144,869 Monitoring of physiological analytes 477 1999
6,272,364 Method and device for predicting physiological values 496 1999
6,326,160 Microprocessors for use in a device for predicting physiological values 435 1999
6,594,514 Device for monitoring of physiological analytes 237 2001
 
Evreka, Inc. (1)
4,436,094 Monitor for continuous in vivo measurement of glucose concentration 435 1982
 
E. HELLER & COMPANY (4)
6,134,461 Electrochemical analyte 900 1998
6,175,752 Analyte monitoring device and methods of use 1138 1998
6,484,046 Electrochemical analyte sensor 730 2000
6,565,509 Analyte monitoring device and methods of use 800 2000
 
EG&G OCEAN PRODUCTS, INC. (1)
4,652,830 Analyzer for comparative measurements of bulk conductivity 42 1985
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (3)
4,671,288 Electrochemical cell sensor for continuous short-term use in tissues and blood 720 1985
4,703,756 Complete glucose monitoring system with an implantable, telemetered sensor module 827 1986
5,650,061 Large amplitude sinusoidal voltammetry 52 1995
 
Health Hero Network, Inc. (1)
6,168,563 Remote health monitoring and maintenance system 737 1999
 
X-Rite, Inc. (1)
5,118,183 Automated strip reader densitometer 63 1990
 
E. I. DU PONT DE NEMOURS AND COMPANY (1)
4,832,814 Electrofusion cell and method of making the same 64 1987
 
CASCADE ENGINEERING, INC. (1)
6,206,282 RF embedded identification device 180 1999
 
Actimed Laboratories, Inc. (1)
5,234,813 Method and device for metering of fluid samples and detection of analytes therein 121 1991
 
E. HELLER & COMPANY, INC. (3)
6,143,164 Small volume in vitro analyte sensor 772 1998
6,120,676 Method of using a small volume in vitro analyte sensor 875 1999
6,576,101 Small volume in vitro analyte sensor 497 1999
 
THE CLEVELAND CLINIC FOUNDATION (1)
4,897,162 Pulse voltammetry 309 1988
 
NATIONAL SCIENCE COUNCIL (1)
6,042,714 Method and chemical sensor for determining concentrations of hydrogen peroxide and its precursor in a liquid 47 1997
 
UNIVERSITY OF WASHINGTON (1)
6,277,641 Methods for analyzing the presence and concentration of multiple analytes using a diffusion-based chemical sensor 63 1999
 
PHASE DYNAMICS, INC. (1)
* 5,748,002 RF probe for montoring composition of substances 43 1996
 
DELSYS PHARMACEUTICAL CORPORATION (1)
6,287,595 Biomedical assay device 62 2000
 
BRITISH TECHNOLOGY GROUP LIMITED (1)
5,691,633 Method of and apparatus for determining a property of a sample 41 1995
 
NEXGEN MICROSYSTEMS, INC. (1)
5,572,159 Voltage-controlled delay element with programmable delay 62 1994
 
KUMETRIX, INC. (1)
5,801,057 Microsampling device and method of construction 356 1996
 
PROVALIS DIAGNOSTICS LIMITED (1)
6,300,142 Device and apparatus for conducting an assay 68 2000
 
GB BIOSCIENCES CORPORATION (1)
5,654,178 Immunoassay for tetrachloroisophthalonitrile (chlorothalonil), its derivatives and breakdown products 36 1995
 
ABBOTT LABORATORIES (11)
5,075,077 Test card for performing assays 183 1988
5,311,426 Apparatus and method for providing assay calibration data 82 1992
5,635,364 Assay verification control for an automated analytical system 88 1994
5,820,551 Strip electrode with screen printing 434 1995
6,129,823 Low volume electrochemical sensor 300 1997
6,087,182 Reagentless analysis of biological samples 95 1998
6,565,738 Diagnostic test for the measurement of analyte in abiological fluid 89 1999
6,377,894 Analyte test instrument having improved calibration and communication processes 250 1999
6,526,298 Method for the non-invasive determination of analytes in a selected volume of tissue 302 2000
6,540,891 Test strip 305 2001
6,600,997 Analyte test instrument having improved calibration and communication processes 130 2001
 
STAT MEDICAL DEVICES, INC. (1)
6,156,051 Lancet having adjustable penetration depth 311 1999
 
SENSOR DIAGNOSTICS, INC. (1)
4,713,347 Measurement of ligand/anti-ligand interactions using bulk conductance 202 1985
 
ICU MEDICAL, INC. (1)
* 5,261,411 Thermal drift correction while continuously monitoring cardiac output 71 1991
 
LIGHTOUCH MEDICAL, INC. (1)
6,044,285 Method for non-invasive measurement of an analyte 137 1998
 
HYBRIVET SYSTEMS, INC. (1)
5,039,618 Test swab cartridge type device and method for detecting lead and cadmium 54 1990
 
GEMALTO SA (1)
6,206,292 Surface-printable RFID-transponders 178 2000
 
METRIKA LABORATORIES, INC. (2)
5,580,794 Disposable electronic assay device 342 1995
5,837,546 Electronic assay device and method 318 1996
 
PHARMACONTROL CORPORATION (1)
4,750,496 Method and apparatus for measuring blood glucose concentration 339 1987
 
ABBOTT DIABETES CARE INC. (24)
6,071,391 Enzyme electrode structure 481 1997
6,251,260 Potentiometric sensors for analytic determination 365 1998
6,281,006 Electrochemical affinity assay 334 1998
6,638,716 Rapid amperometric verification of PCR amplification of DNA 63 1998
6,294,281 Biological fuel cell and method 267 1998
6,338,790 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 536 1999
6,299,757 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 515 1999
6,461,496 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 704 1999
6,616,819 Small volume in vitro analyte sensor and methods 509 1999
6,156,173 Enzyme electrode structure 108 2000
6,551,494 Small volume in vitro analyte sensor 483 2000
6,592,745 Method of using a small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 426 2000
6,618,934 Method of manufacturing small volume in vitro analyte sensor 663 2000
6,654,625 Mass transport limited in vivo analyte sensor 596 2000
6,591,125 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 729 2000
6,579,690 Blood analyte monitoring through subcutaneous measurement 728 2000
6,503,381 Biosensor 350 2000
6,329,161 Subcutaneous glucose electrode 787 2000
6,605,200 Polymeric transition metal complexes and uses thereof 408 2000
6,605,201 Transition metal complexes with bidentate ligand having an imidazole ring and sensor constructed therewith 412 2000
6,607,658 Integrated lancing and measurement device and analyte measuring methods 446 2000
6,560,471 Analyte monitoring device and methods of use 750 2001
6,623,501 Reusable ceramic skin-piercing device 363 2001
6,531,239 Biological fuel cell and methods 70 2001
 
INVERNESS MEDICAL TECHNOLOGY, INC. (3)
5,708,247 Disposable glucose test strips, and methods and compositions for making same 547 1996
5,951,836 Disposable glucose test strip and method and compositions for making same 400 1998
6,241,862 Disposable test strips with integrated reagent/blood separation layer 376 1999
 
INVERNESS MEDICAL SWITZERLAND GMBH (1)
5,141,868 Device for use in chemical test procedures 593 1989
 
KYOTO DAIICHI KAGAKU CO., LTD. (3)
5,720,862 Sensor and production method of and measurement method using the same 354 1996
6,377,896 Method and apparatus for determination of a substance coexisting with another substance 52 1999
6,349,230 Blood measuring instrument 58 2000
 
KROHNE MESSTECHNIK GMBH (1)
6,401,532 Fill level gauge 39 2001
 
BOEHRINGER, A CORP. OF GERMANY (1)
4,510,383 Device for the optical identification of a coding on a diagnostic test strip 66 1982
 
PANASONIC HEALTHCARE CO., LTD. (1)
6,599,406 Concentration measuring apparatus, test strip for the concentration measuring apparatus, biosensor system and method for forming terminal on the test strip 161 2000
 
NOKIA TECHNOLOGIES OY (1)
6,295,506 Measurement apparatus 528 1998
 
Seiko Instruments & Electronics Ltd. (1)
4,789,804 Analytical device and method utilizing a piezoelectric crystal biosensor 133 1986
 
Visionary Medical Products, Inc. (3)
5,728,074 Pen-type injector with a microprocessor and blood characteristic monitor 270 1994
5,593,390 Medication delivery device with a microprocessor and characteristic monitor 437 1995
5,925,021 Medication delivery device with a microprocessor and characteristic monitor 533 1997
 
OSMETECH TECHNOLOGY INC. (1)
6,013,170 Detection of analytes using reorganization energy 106 1998
 
ROCHE DIABETES CARE, INC. (31)
4,731,726 Patient-operated glucose monitor and diabetes management system 1025 1986
4,797,256 Registration device for blood test strips 83 1987
5,053,199 Electronically readable information carrier 159 1989
5,128,015 Method and apparatus for amperometric diagnostic analysis 292 1989
4,963,814 Regulated bifurcated power supply 59 1989
4,999,582 Biosensor electrode excitation circuit 212 1989
4,999,632 Analog to digital conversion with noise reduction 80 1989
5,243,516 Biosensing instrument and method 147 1989
5,232,668 Test strip holding and reading mechanism for a meter 134 1991
5,246,858 Apparatus and method for analyzing a body fluid 73 1991
5,108,564 Method and apparatus for amperometric diagnostic analysis 446 1991
5,371,687 Glucose test data acquisition and management system 469 1992
5,284,770 Meter verification method and apparatus 40 1993
5,385,846 Biosensor and method for hematocrit determination 163 1993
5,352,351 Biosensing meter with fail/safe procedures to prevent erroneous indications 500 1993
5,405,511 Biosensing meter with ambient temperature estimation method and system 220 1993
5,413,690 Potentiometric biosensor and the method of its use 324 1993
5,379,214 Method for reading the concentration of a medically significant component of a biological fluid from a test strip 83 1993
5,437,999 Electrochemical sensor 641 1994
5,594,906 Zero power receive detector for serial data interface 181 1994
5,438,271 Biosensing meter which detects proper electrode engagement and distinguishes sample and check strips 340 1994
5,762,770 Electrochemical biosensor test strip 318 1995
6,162,639 Embossed test strip system 203 1998
6,413,395 Biosensor apparatus 53 1999
6,627,057 Microsphere containing sensor 48 1999
6,413,213 Subscription based monitoring system and method 58 2000
6,645,359 Biosensor 87 2000
6,540,890 Biosensor 64 2000
6,447,657 Biosensor 78 2000
6,544,474 Device for determination of an analyte in a body fluid using small sample sizes 57 2001
* 7,018,843 Instrument 57 2001
 
MILES INC. (4)
4,938,860 Electrode for electrochemical sensors 320 1985
4,806,311 Multizone analytical element having labeled reagent concentration zone 166 1985
4,806,312 Multizone analytical element having detectable signal concentrating zone 123 1985
5,250,439 Use of conductive sensors in diagnostic assays 353 1992
 
INVERNESS MEDICAL - BIOSTAR INC. (1)
5,639,671 Methods for optimizing of an optical assay device 89 1995
 
NOVO NORDISK A/S (1)
5,269,891 Method and apparatus for determination of a constituent in a fluid 412 1993
 
AMP INCORPORATED, A CORPORATION OF PENNSYLVANIA (1)
4,648,665 Electronic key assemblies 42 1985
 
QUEEN MARY & WESTFIELD COLLEGE (1)
6,300,123 Sensor employing impedance measurements 48 1999
 
BECTON, DICKINSON AND COMPANY (2)
4,628,193 Code reading operations supervisor 148 1980
4,703,017 Solid phase assay with visual readout 304 1984
 
DADE BEHRING INC. (1)
4,517,291 Biological detection process using polymer-coated electrodes 93 1983
 
TALL OAK VENTURES (1)
6,153,069 Apparatus for amperometric Diagnostic analysis 359 1995
 
NANOGEN, INC. (1)
5,605,662 Active programmable electronic devices for molecular biological analysis and diagnostics 652 1993
 
CYTYC CORPORATION (1)
6,394,952 Point of care diagnostic systems 145 1998
 
3M INNOVATIVE PROPERTIES COMPANY (2)
6,203,952 Imaged article on polymeric substrate 110 1999
6,399,258 Method for patterning thin films 49 2001
 
LIFEHEALTH, LLC (1)
* 5,232,667 Temperature control for portable diagnostic system using a non-contact temperature probe 58 1992
 
Affymetrix, Inc. (1)
5,922,591 Integrated nucleic acid diagnostic device 558 1996
 
TECAN TRADING AG (1)
6,143,247 Affinity binding-based system for detecting particulates in a fluid 195 1997
 
Packard Instrument Company (1)
6,538,735 Method and apparatus for producing and measuring light and for determining the amounts of analytes in microplate wells 41 2000
 
CONMED CORPORATION (1)
5,921,925 Biomedical electrode having a disposable electrode and a reusable leadwire adapter that interfaces with a standard leadwire connector 79 1997
 
HOUSTON ADVANCED RESEARCH CENTER (1)
5,532,128 Multi-site detection apparatus 206 1994
 
Nipro Diagnostics, Inc. (6)
5,296,192 Diagnostic test strip 81 1992
6,284,550 Diagnostic sanitary test strip 71 1999
6,525,330 Method of strip insertion detection 81 2001
6,541,266 Method for determining concentration of an analyte in a test strip 218 2001
6,562,625 Distinguishing test types through spectral analysis 70 2001
6,743,635 System and methods for blood glucose sensing 390 2002
 
Relia Diagnostic Systems, Inc. (1)
6,136,610 Method and apparatus for performing a lateral flow assay 101 1998
 
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (1)
5,611,900 Microbiosensor used in-situ 318 1995
 
LIFECAN, INC. (1)
6,420,128 Test strips for detecting the presence of a reduced cofactor in a sample and method for using the same 133 2000
 
ELECTROSYNTHESIS COMPANY, INC., THE (1)
5,437,772 Portable lead detector 65 1993
 
DERMAL DEVICES INC. (1)
5,890,489 Method for non-invasive determination of glucose in body fluids 64 1996
 
DR. HOLGER KIESEWETTER (1)
4,547,735 Instrument for measuring the hematocrit value of blood 58 1983
 
INVERNESS MEDICAL TECHNOLOGY (1)
5,989,917 Glucose monitor and test strip containers for use in same 135 1996
 
Boehringer Mannheim GmbH (19)
4,477,575 Process and composition for separating plasma or serum from whole blood 269 1981
4,476,149 Process for the production of an analysis test strip 85 1982
4,592,893 Analysis test strip 101 1984
4,578,716 Method of and apparatus for making a test strip and a test strip made by such method 57 1984
4,676,653 Apparatus for determining the diffuse reflectivity of a sample surface of small dimensions 81 1984
4,816,224 Device for separating plasma or serum from whole blood and analyzing the same 152 1987
4,834,234 Container for test strips 92 1988
5,035,862 Analytical system for the determination of a component of a fluid 48 1988
5,413,764 Test carrier analysis system 56 1990
5,143,694 Test strip evaluating instrument for multiple test strips 69 1990
5,122,244 Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor 213 1991
5,281,395 Test carrier analysis system 183 1991
5,286,362 Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor 427 1993
5,424,035 Test strip analysis system 140 1994
5,489,414 System for analyzing compounds contained in liquid samples 182 1994
5,556,789 Device for the simultaneous determination of several analytes 51 1994
5,445,967 Method for analyzing a component of a liquid sample 66 1994
5,645,798 Test elements in sealed chambers for analyzing compounds contained in liquid samples 83 1995
5,757,666 System for analyzing compounds contained liquid samples 90 1996
 
LONZA GROUP AG (1)
5,604,110 Binding assay device 57 1995
 
Medisense, Inc. (7)
4,545,382 Sensor for components of a liquid mixture 641 1982
4,711,245 Sensor for components of a liquid mixture 567 1984
5,509,410 Strip electrode including screen printing of a single layer 599 1994
5,682,884 Strip electrode with screen printing 453 1994
5,727,548 Strip electrode with screen printing 404 1995
5,628,890 Electrochemical sensor 784 1995
5,849,174 Electrodes and their use in analysis 195 1997
 
OttoSensors Corporation (1)
4,682,602 Probe for medical application 258 1985
 
LRE TECHNOLOGY PARTNER GMBH (3)
5,904,898 Test strip 73 1998
6,315,951 Test strip measuring system 53 1999
6,525,549 Method for determining the concentration of a substance in a liquid by measuring electrical current in a test strip 56 2000
 
PANASONIC CORPORATION (1)
5,264,103 Biosensor and a method for measuring a concentration of a substrate in a sample 572 1992
 
QUESTSTAR MEDICAL, INC. (1)
5,279,294 Medical diagnostic system 686 1990
 
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (1)
5,670,031 Electrochemical sensor 299 1995
 
FA. LPKF CAD/CAM SYSTEME GMBH (1)
5,576,073 Method for patterned metallization of a substrate surface 61 1995
 
ACUSON CORPORATION (1)
6,300,961 Ultrasonic system and method for processing data 38 1999
 
SMITHKLINE DIAGNOSTICS, INC., A CORP. OF DE (1)
4,935,106 Ion selective/enzymatic electrode medical analyzer device and method of use 51 1985
 
EURUS LLC (1)
5,019,974 Diabetes management system and apparatus 691 1990
 
HITACHI, LTD. (1)
5,470,533 Test strip supply apparatus and analyzer using same 49 1993
 
UMM Electronics, Inc. (1)
6,150,124 Method for passively determining the application of a sample fluid on an analyte strip 50 1999
 
LPKF LASER & ELECTRONICS AG (1)
5,593,739 Method of patterned metallization of substrate surfaces 54 1996
 
CUMMINS FILTRATION INC. (1)
2004/0094,459 LIQUID FILTER WITH SEPARATE AND CALIBRATED VAPOR RELEASE 1 2003
 
DISETRONIC LICENSING AG (2)
5,411,647 Techniques to improve the performance of electrochemical sensors 684 1994
5,695,623 Glucose measuring device 514 1994
 
MARCONI COMMUNICATIONS LTD. (1)
6,576,461 Electrochemical affinity assay 60 2001
 
I-STAT CORPORATION (3)
5,096,669 Disposable sensing device for real time fluid analysis 435 1988
4,954,087 Static-free interrogating connector for electric components 69 1990
5,112,455 Method for analytically utilizing microfabricated sensors during wet-up 182 1990
 
CLINICAL DIAGNOSTIC SYSTEMS INC. (4)
4,323,536 Multi-analyte test device 135 1980
4,413,407 Method for forming an electrode-containing device with capillary transport between electrodes 83 1981
4,552,458 Compact reflectometer 118 1983
5,126,952 Bar coding calibration 36 1991
 
FIRST NATIONAL BANK OF BOSTON, THE (2)
4,686,479 Apparatus and control kit for analyzing blood sample values including hematocrit 84 1985
4,759,828 Glucose electrode and method of determining glucose 468 1987
 
OPTIKOS CORPORATION (1)
6,226,081 Optical height of fill detection system and associated methods 51 1998
 
MAGELLAN DIAGNOSTICS, INC. (1)
6,391,558 Electrochemical detection of nucleic acid sequences 91 2000
 
CIBA CORNING DIAGNOSTICS CORP. (2)
5,066,372 Unitary multiple electrode sensor 84 1990
5,421,189 Electrical connection system for electrochemical sensors 51 1994
 
Hygeia Sciences, Inc. (1)
5,141,850 Porous strip form assay device method 194 1990
 
ASULAB S.A. (1)
5,395,504 Electrochemical measuring system with multizone sensors 403 1994
 
SIEMENS AKTIENGESELLSCHAFT (2)
4,477,314 Method for determining sugar concentration 339 1983
4,919,770 Method for determining the concentration of electro-chemically convertible substances 146 1986
 
INSTITUT FUR CHEMO-UND BIOSENSORIK MUNSTER E.V. (1)
* 6,004,442 Analyte-selective sensor 77 1997
 
GENZYME CORPORATION (1)
5,656,502 Test strip holder and method of use 95 1995
 
PBI TECHNOLOGY, INC. (1)
6,102,872 Glucose detector and method 77 1998
 
LIFESCAN, IC., A CORP. OF CA. (1)
4,976,724 Lancet ejector mechanism 284 1989
 
Microcor, Inc. (2)
5,526,808 Method and apparatus for noninvasively determining hematocrit 82 1995
5,642,734 Method and apparatus for noninvasively determining hematocrit 96 1996
 
CAMBRIDGE LIFE SCIENCES PLC (2)
4,970,145 Immobilized enzyme electrodes 365 1988
5,846,744 Sensors based on polymer transformation 232 1996
 
Biologix, Inc. (2)
4,940,945 Interface circuit for use in a portable blood chemistry measuring apparatus 65 1987
* 4,929,426 Portable blood chemistry measuring apparatus 160 1988
 
FUJI ELECTRIC CO., LTD. (1)
4,407,959 Blood sugar analyzing apparatus 236 1981
 
BAYER HEALTHCARE LLC (1)
5,630,986 Dispensing instrument for fluid monitoring sensors 325 1995
 
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (2)
4,805,624 Low-potential electrochemical redox sensors 343 1987
6,271,044 Method and kit for detecting an analyte 46 1998
 
Dragerwerk Aktiengesellschaft (1)
4,499,423 Circuit arrangement for correction of a sensor output 39 1981
 
ASSURANCE BIOTECH LLC (1)
6,514,769 Multiple analyte assay device with sample integrity monitoring system 74 1999
 
BAYER AKTIENGESELLSCHAFT (1)
5,916,156 Electrochemical sensors having improved selectivity and enhanced sensitivity 181 1997
 
SHIMADZU CORPORATION (1)
4,820,399 Enzyme electrodes 421 1985
 
Cardiac Pacemakers, Inc. (1)
4,679,562 Glucose sensor 291 1986
 
University Patents, Inc. (1)
4,440,175 Membrane electrode for non-ionic species 250 1981
 
TECHNIMED CORPORATION (1)
4,877,580 Assay kit including an analyte test strip and a color comparator 82 1988
 
MIGRATA U.K. LIMITED (1)
4,654,197 Cuvette for sampling and analysis 349 1984
 
NIPPON TELEGRAPH AND TELEPHONE CORPORATION (1)
5,389,215 Electrochemical detection method and apparatus therefor 84 1993
 
LXN CORPORATION (1)
5,885,839 Methods of determining initiation and variable end points for measuring a chemical reaction 52 1997
 
GENETICS INSTITUTE, INC. (1)
4,820,636 Electrochemical assay for cis-diols 68 1986
 
BAYER CORPORATION (10)
5,552,116 Test strip pick-up mechanism in automated analyzer 45 1995
5,620,579 Apparatus for reduction of bias in amperometric sensors 238 1995
5,665,215 Method and apparatus for making predetermined events with a biosensor 75 1995
5,723,284 Control solution and method for testing the performance of an electrochemical device for determining the concentration of an analyte in blood 202 1996
5,653,863 Method for reducing bias in amperometric sensors 510 1996
5,883,378 Apparatus and methods for transmitting electrical signals indicative of optical interactions between a light beam and a flowing suspension of particles 79 1996
5,856,195 Method and apparatus for calibrating a sensor element 185 1996
5,798,031 Electrochemical biosensor 338 1997
6,391,645 Method and apparatus for correcting ambient temperature effect in biosensors 62 1997
6,246,966 Method and apparatus for data management authentication in a clinical analyzer 50 1998
 
Imperial Chemical Industries PLC (1)
4,935,105 Methods of operating enzyme electrode sensors 278 1989
 
PANASONIC HEALTHCARE HOLDINGS CO., LTD. (11)
5,582,697 Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same 567 1995
5,575,895 Biosensor and method for producing the same 407 1995
5,650,062 Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same 416 1995
6,004,441 Biosensor 298 1997
6,225,078 Method for quantitative measurement of a substrate 167 1998
6,258,254 Biosensor 166 1998
6,656,702 Biosensor containing glucose dehydrogenase 177 1999
RE36991 Biosensor and method for producing the same 181 1999
6,309,526 Biosensor 206 1999
6,340,428 Device and method for determining the concentration of a substrate 63 1999
6,342,364 Cholesterol sensor and method of determining cholesterol 37 2001
 
BECKMAN COULTER, INC. (3)
5,344,754 Assay timed by electrical resistance change and test strip 76 1993
5,554,531 Device for performing timed assay by electrical resistance change 76 1995
6,061,128 Verification device for optical clinical assay systems 151 1998
 
RUBICON INVESTMENTS, INC. (1)
6,128,519 System and method for measuring a bioanalyte such as lactate 80 1998
 
THERASENSE, INC. (3)
6,103,033 Process for producing an electrochemical biosensor 879 1998
6,162,611 Subcutaneous glucose electrode 741 2000
6,514,718 Subcutaneous glucose electrode 582 2001
 
ALZA CORPORATION (1)
6,091,975 Minimally invasive detecting device 620 1998
 
ORASURE TECHNOLOGIES, INC. (1)
5,112,758 Treating body fluids for diagnostic testing 43 1988
 
Sensors for Medicine and Science, Inc. (1)
6,330,464 Optical-based sensing devices 431 1999
 
ESA BIOSCIENCES, INC. (1)
5,873,990 Handheld electromonitor device 175 1996
 
SPECTRUM SYSTEMS, INC. (1)
5,508,200 Method and apparatus for conducting multiple chemical assays 227 1992
 
ARKRAY, INC. (2)
6,180,062 Device for analyzing a sample 55 1999
6,576,117 Method and apparatus for electrochemical measurement using statistical technique 334 2001
 
THOMSON-CSF (1)
4,420,564 Blood sugar analyzer having fixed enzyme membrane sensor 355 1981
 
CALIFORNIA INSTITUTE OF TECHNOLOGY (3)
5,788,833 Sensors for detecting analytes in fluids 117 1996
5,911,872 Sensors for detecting analytes in fluids 105 1997
6,170,318 Methods of use for sensor based fluid detection devices 215 1998
 
MEDTRONIC CRYOCATH LP (1)
5,232,516 Thermoelectric device with recuperative heat exchangers 151 1991
 
SIEMENS MEDICAL SOLUTIONS USA, INC. (2)
5,971,923 Ultrasound system and method for interfacing with peripherals 83 1997
6,262,749 Ultrasonic system and method for data transfer, storage and/or processing 47 1997
 
HYPOGUARD LIMITED (1)
5,494,638 Support membrane 57 1994
 
AT&T Bell Laboratories (1)
5,353,351 Secure teleconferencing 74 1992
 
JPMORGAN CHASE BANK, NATIONAL ASSOCIATION (1)
5,597,532 Apparatus for determining substances contained in a body fluid 142 1994
 
RIGAKU CORPORATION (1)
6,570,390 Method for measuring surface leakage current of sample 33 2001
 
MALLINCKRODT SENSOR SYSTEMS, INC., (1)
4,734,184 Self-activating hydratable solid-state electrode apparatus 122 1987
 
Hosiden Electronics Co., Ltd. (1)
4,810,203 Electrical connector 56 1987
 
Nova Biomedical Corporation (3)
4,975,647 Controlling machine operation with respect to consumable accessory units 197 1988
6,258,229 Disposable sub-microliter volume sensor and method of making 264 1999
6,287,451 Disposable sensor and method of making 159 1999
 
SYVA COMPANY (1)
5,439,826 Method of distinguishing among strips for different assays in an automated instrument 64 1988
 
ROCHE OPERATIONS LTD. (4)
5,366,609 Biosensing meter with pluggable memory key 464 1993
5,997,817 Electrochemical biosensor test strip 450 1997
6,270,637 Electrochemical biosensor test strip 293 1999
6,645,368 Meter and method of using the meter for determining the concentration of a component of a fluid 214 2000
 
ROCHE DIAGNOSTICS CORPORATION (3)
4,642,295 Methods of determining fructosamine levels in blood samples 55 1982
5,288,636 Enzyme electrode system 510 1990
5,508,171 Assay method with enzyme electrode system 474 1994
 
GENERAL ELECTRIC COMPANY (1)
4,865,873 Electroless deposition employing laser-patterned masking layer 69 1987
 
MOLECULAR DEVICES CORPORATION (2)
4,849,330 Photoresponsive redox detection and discrimination 78 1985
4,956,275 Migratory detection immunoassay 106 1987
 
MILES LABORATORIES, INC. (1)
4,714,874 Test strip identification and instrument calibration 195 1985
 
BOC GROUP, INC., THE (1)
4,407,290 Blood constituent measuring device and method 308 1981
 
ROCHE DIAGNOSTICS OPERATIONS, INC. (4)
5,526,111 Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control 48 1993
5,686,659 Fluid dose flow and coagulation sensor for medical instrument 61 1995
5,710,622 Fluid dose, flow and coagulation sensor for medical instrument 36 1995
5,832,921 Analog heater control for medical instrument 38 1995
 
ST. JUDE MEDICAL, INC. (1)
4,795,542 Electrochemical concentration detector device 124 1986
 
Moorlodge Ventures Limited (1)
6,660,141 Electrochemical sensor 17 2001
 
RHEONIX, INC. (1)
6,358,752 Liposome-enhanced test device and method 56 1999
 
ORTHO PHARMACEUTICAL CORPORATION (1)
5,179,288 Apparatus and method for measuring a bodily constituent 61 1991
 
SEGARS CALIFORNIA PARTNERS, LP (1)
5,220,920 Electrochemical measurement system having interference reduction circuit 73 1991
 
MICROFAB TECHNOLOGIES, INC. (1)
5,658,802 Method and apparatus for making miniaturized diagnostic arrays 218 1995
 
Apex Biotechnology Corp. (1)
6,491,803 Test strip and biosensor incorporating with nanometer metal particles 71 2001
 
Innovative Biotechnologies, Inc. (1)
6,159,745 Interdigitated electrode arrays for liposome-enhanced immunoassay and test device 51 1999
 
WAVESENSE, INC. (1)
6,136,549 systems and methods for performing magnetic chromatography assays 93 1999
 
SIEMENS HEALTHCARE DIAGNOSTICS INC. (7)
5,477,326 Spectrophotometer arrangement with multi-detector readhead 57 1994
5,569,608 Quantitative detection of analytes on immunochromatographic strips 135 1995
5,691,486 Apparatus and methods for selecting a variable number of test sample aliquots to mix with respective reagents 59 1996
5,719,667 Apparatus for filtering a laser beam in an analytical instrument 83 1996
5,745,308 Methods and apparatus for an optical illuminator assembly and its alignment 92 1996
5,945,341 System for the optical identification of coding on a diagnostic test strip 96 1996
6,316,264 Test strip for the assay of an analyte in a liquid sample 56 1999
 
Silver Lake Corporation (1)
6,287,875 Internally referenced competitive assays 40 2000
 
Keith & Rumph Inventors, Inc. (1)
6,126,609 Apparatus for taking blood samples from a patient 31 1998
 
LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (1)
5,698,083 Chemiresistor urea sensor 94 1995
 
CASE WESTERN RESERVE UNIVERSITY (1)
4,571,292 Apparatus for electrochemical measurements 447 1982
 
OPTISCAN, INC. (1)
5,515,847 Self-emission noninvasive infrared spectrophotometer 165 1994
 
QBC DIAGNOSTICS, INC. (4)
5,635,362 Assay of blood or other biologic samples for target analytes 54 1994
5,834,217 Assay of blood or other biologic samples for target analytes 55 1996
5,759,794 Assay of blood or other biologic samples for target analytes 46 1996
5,776,710 Assay of blood or other biologic samples for target analytes 53 1996
 
LIFESCAN, INC. (62)
4,935,346 Minimum procedure system for the determination of analytes 276 1986
5,049,487 Automated initiation of timing of reflectance readings 459 1988
5,059,394 Analytical device for the automated determination of analytes in fluids 369 1988
5,179,005 Minimum procedure system for the determination of analytes 245 1988
5,306,623 Visual blood glucose concentration test strip 244 1991
5,187,100 Dispersion to limit penetration of aqueous solutions into a membrane 205 1991
5,418,142 Glucose test strip for whole blood 217 1992
5,304,468 Reagent test strip and apparatus for determination of blood glucose 640 1993
5,426,032 No-wipe whole blood glucose test strip 313 1993
5,453,360 Oxidative coupling dye for spectrophotometric quantitive analysis of analytes 157 1994
5,515,170 Analyte detection device having a serpentine passageway for indicator strips 182 1994
5,526,120 Test strip with an asymmetrical end insuring correct insertion for measuring 384 1994
5,563,031 Highly stable oxidative coupling dye for spectrophotometric determination of analytes 164 1994
6,335,203 Optically readable strip for analyte detection having on-strip orientation index 153 1994
5,563,042 Whole blood glucose test strip 241 1995
6,395,227 Test strip for measuring analyte concentration over a broad range of sample volume 131 1995
5,620,863 Blood glucose strip having reduced side reactions 167 1995
5,922,530 Stable coupling dye for photometric determination of analytes 125 1995
5,605,837 Control solution for a blood glucose monitor 177 1996
5,780,304 Method and apparatus for analyte detection having on-strip standard 192 1996
5,843,691 Visually-readable reagent test strip 180 1996
6,168,957 Diagnostic test strip having on-strip calibration 175 1997
5,789,255 Blood glucose strip having reduced sensitivity to hematocrit 160 1997
5,843,692 Automatic initiation of a time interval for measuring glucose concentration in a sample of whole blood 197 1997
5,968,760 Temperature-Independent Blood Glucose Measurement 156 1997
6,284,125 Electrochemical cell 194 1998
6,045,567 Lancing device causing reduced pain 222 1999
6,197,040 Lancing device having a releasable connector 188 1999
6,179,979 Electrochemical cell 142 1999
6,200,773 Diagnostics based on tetrazolium compounds 143 1999
6,174,420 Electrochemical cell 137 1999
6,268,162 Reflectance measurement of analyte concentration with automatic initiation of timing 196 1999
6,193,873 Sample detection to initiate timing of an electrochemical assay 321 1999
6,521,182 Fluidic device for medical diagnostics 156 1999
6,261,519 Medical diagnostic device with enough-sample indicator 172 1999
6,379,513 Sensor connection means 67 1999
6,454,921 Electrochemical cell 48 1999
6,218,571 8-(anilino)-1-naphthalenesulfonate analogs 115 1999
6,475,372 Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations 250 2000
6,485,923 Reagent test strip for analyte determination having hemolyzing agent 134 2000
6,325,917 Method and apparatus for automatic analysis 44 2000
6,571,651 Method of preventing short sampling of a capillary or wicking fill device 169 2000
6,488,827 Capillary flow control in a medical diagnostic device 143 2000
6,592,744 Method of filling an amperometric cell 115 2000
6,444,115 Electrochemical method for measuring chemical reaction rates 184 2000
6,632,349 Hemoglobin sensor 194 2000
6,638,415 Antioxidant sensor 141 2000
6,413,410 Electrochemical cell 223 2000
6,475,360 Heated electrochemical cell 180 2000
6,555,061 Multi-layer reagent test strip 186 2000
6,521,110 Electrochemical cell 204 2000
6,531,322 Visual blood glucose test strip 135 2000
6,558,528 Electrochemical test strip cards that include an integral dessicant 185 2000
6,512,986 Method for automated exception-based quality control compliance for point-of-care devices 121 2000
6,489,133 Apparatus for determinating the concentration of glucose in whole blood 135 2001
6,549,796 Monitoring analyte concentration using minimally invasive devices 348 2001
6,501,976 Percutaneous biological fluid sampling and analyte measurement devices and methods 175 2001
6,576,416 Analyte measurement device and method of use 168 2001
6,491,870 Optically readable strip for analyte detection having on-strip orientation index 128 2001
6,689,411 Solution striping system 141 2001
6,676,995 Solution striping system 156 2002
6,572,822 Visual blood glucose test strip 130 2002
 
MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (6)
4,897,173 Biosensor and method for making the same 465 1987
5,120,420 Biosensor and a process for preparation thereof 676 1989
5,266,179 Quantitative analysis method and its system using a disposable sensor 718 1991
5,192,415 Biosensor utilizing enzyme and a method for producing the same 430 1992
5,658,443 Biosensor and method for producing the same 152 1994
5,948,289 Laser beam machining method 51 1996
 
MATRIA HEALTHCARE, LLC (1)
5,182,707 Apparatus for recording reagent test strip data by comparison to color lights on a reference panel 252 1990
 
YASSINZADEH, ZIA (1)
5,700,695 Sample collection and manipulation method 342 1994
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
ROCHE DIABETES CARE, INC. (3)
8,148,164 System and method for determining the concentration of an analyte in a sample fluid 0 2009
8,298,828 System and method for determining the concentration of an analyte in a sample fluid 2 2012
8,586,373 System and method for determining the concentration of an analyte in a sample fluid 0 2012
 
CILAG GMBH INTERNATIONAL (3)
8,551,320 System and method for measuring an analyte in a sample 0 2009
8,932,445 Systems and methods for improved stability of electrochemical sensors 0 2010
8,617,370 Systems and methods of discriminating between a control sample and a test fluid using capacitance 0 2010
 
ROCHE OPERATIONS LTD. (3)
* 7,981,363 System and method for analyte measurement 9 2008
* 8,691,152 System and method for analyte measurement 0 2012
* 2012/0135,508 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT 17 2012
 
LIFESCAN, INC. (10)
8,529,751 Systems and methods for discriminating control solution from a physiological sample 0 2006
8,778,168 Systems and methods of discriminating control solution from a physiological sample 0 2008
8,603,768 System and method for measuring an analyte in a sample 0 2009
8,486,649 System and method for measuring an analyte in a sample 0 2009
8,877,034 Systems, devices, and methods for measuring whole blood hematocrit based on initial fill velocity 0 2009
8,101,065 Systems, devices, and methods for improving accuracy of biosensors using fill time 4 2009
8,449,740 Systems and methods for discriminating control solution from a physiological sample 0 2010
8,623,198 Systems, devices, and methods for improving accuracy of biosensors using fill time 2 2010
8,916,040 System and method for measuring an analyte in a sample 0 2012
8,709,739 System and method for measuring an analyte in a sample 0 2012
 
BAYER HEALTHCARE LLC (4)
8,401,873 Health data management device 1 2008
8,649,997 Systems and methods for predicting ambient temperature in a fluid analyte meter 1 2009
8,617,381 System and apparatus for determining temperatures in a fluid analyte system 1 2010
9,097,650 System and apparatus for determining temperatures in a fluid analyte system 0 2013
* Cited By Examiner

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