US Patent No: 7,390,667

Number of patents in Portfolio can not be more than 2000

System and method for analyte measurement using AC phase angle measurements

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Abstract

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A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ROCHE DIABETES CARE, INC.INDIANAPOLIS, IN, US869
ROCHE OPERATIONS LTD.HAMILTON59

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beaty, Terry A Indianapolis, IN 28 1274
Burke, David W Carmel, IN 48 2756
Kuhn, Lance S Fishers, IN 20 1659
Svetnik, Vladimir Morristown, NJ 16 1866

Cited Art Landscape

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4,420,564 Blood sugar analyzer having fixed enzyme membrane sensor 375 1981
 
CALIFORNIA INSTITUTE OF TECHNOLOGY (3)
5,788,833 Sensors for detecting analytes in fluids 121 1996
5,911,872 Sensors for detecting analytes in fluids 108 1997
6,170,318 Methods of use for sensor based fluid detection devices 225 1998
 
MEDTRONIC CRYOCATH LP (1)
5,232,516 Thermoelectric device with recuperative heat exchangers 157 1991
 
SIEMENS MEDICAL SOLUTIONS USA, INC. (2)
5,971,923 Ultrasound system and method for interfacing with peripherals 85 1997
6,262,749 Ultrasonic system and method for data transfer, storage and/or processing 51 1997
 
Hypoguard Limited (1)
5,494,638 Support membrane 57 1994
 
AT&T Bell Laboratories (1)
5,353,351 Secure teleconferencing 76 1992
 
JPMORGAN CHASE BANK, N.A. (1)
5,597,532 Apparatus for determining substances contained in a body fluid 144 1994
 
RIGAKU CORPORATION (1)
6,570,390 Method for measuring surface leakage current of sample 33 2001
 
Mallinckrodt Sensor Systems Inc. (1)
4,734,184 Self-activating hydratable solid-state electrode apparatus 123 1987
 
Hosiden Electronics Co., Ltd. (1)
4,810,203 Electrical connector 56 1987
 
Nova Biomedical Corporation (3)
4,975,647 Controlling machine operation with respect to consumable accessory units 200 1988
6,258,229 Disposable sub-microliter volume sensor and method of making 274 1999
6,287,451 Disposable sensor and method of making 169 1999
 
SYVA COMPANY (1)
5,439,826 Method of distinguishing among strips for different assays in an automated instrument 65 1988
 
ROCHE OPERATIONS LTD. (4)
5,366,609 Biosensing meter with pluggable memory key 485 1993
5,997,817 Electrochemical biosensor test strip 472 1997
6,270,637 Electrochemical biosensor test strip 301 1999
6,645,368 Meter and method of using the meter for determining the concentration of a component of a fluid 235 2000
 
ROCHE DIAGNOSTICS CORPORATION (3)
4,642,295 Methods of determining fructosamine levels in blood samples 55 1982
5,288,636 Enzyme electrode system 537 1990
5,508,171 Assay method with enzyme electrode system 498 1994
 
GENERAL ELECTRIC COMPANY (1)
4,865,873 Electroless deposition employing laser-patterned masking layer 74 1987
 
MOLECULAR DEVICES CORPORATION (2)
4,849,330 Photoresponsive redox detection and discrimination 78 1985
4,956,275 Migratory detection immunoassay 107 1987
 
Miles Laboratories, Inc. (1)
4,714,874 Test strip identification and instrument calibration 202 1985
 
The BOC Group, Inc. (1)
4,407,290 Blood constituent measuring device and method 311 1981
 
ROCHE DIAGNOSTICS OPERATIONS, INC. (4)
5,526,111 Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control 48 1993
5,686,659 Fluid dose flow and coagulation sensor for medical instrument 61 1995
5,710,622 Fluid dose, flow and coagulation sensor for medical instrument 36 1995
5,832,921 Analog heater control for medical instrument 39 1995
 
ST. JUDE MEDICAL, INC. (1)
4,795,542 Electrochemical concentration detector device 139 1986
 
Moorlodge Ventures Limited (1)
6,660,141 Electrochemical sensor 17 2001
 
RHEONIX, INC. (1)
6,358,752 Liposome-enhanced test device and method 57 1999
 
Ortho Pharmaceutical Corporation (1)
5,179,288 Apparatus and method for measuring a bodily constituent 62 1991
 
Segars California Partners, LP (1)
5,220,920 Electrochemical measurement system having interference reduction circuit 74 1991
 
MicroFab Technologies, Inc. (1)
5,658,802 Method and apparatus for making miniaturized diagnostic arrays 221 1995
 
APEX BIOTECHNOLOGY CORP. (1)
6,491,803 Test strip and biosensor incorporating with nanometer metal particles 72 2001
 
Innovative Biotechnologies, Inc. (1)
6,159,745 Interdigitated electrode arrays for liposome-enhanced immunoassay and test device 52 1999
 
WAVESENSE, INC. (1)
6,136,549 systems and methods for performing magnetic chromatography assays 93 1999
 
SIEMENS HEALTHCARE DIAGNOSTICS INC. (7)
5,477,326 Spectrophotometer arrangement with multi-detector readhead 60 1994
5,569,608 Quantitative detection of analytes on immunochromatographic strips 141 1995
5,691,486 Apparatus and methods for selecting a variable number of test sample aliquots to mix with respective reagents 59 1996
5,719,667 Apparatus for filtering a laser beam in an analytical instrument 83 1996
5,745,308 Methods and apparatus for an optical illuminator assembly and its alignment 93 1996
5,945,341 System for the optical identification of coding on a diagnostic test strip 98 1996
6,316,264 Test strip for the assay of an analyte in a liquid sample 57 1999
 
Silver Lake Corporation (1)
6,287,875 Internally referenced competitive assays 40 2000
 
Keith & Rumph Inventors, Inc. (1)
6,126,609 Apparatus for taking blood samples from a patient 31 1998
 
LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (1)
5,698,083 Chemiresistor urea sensor 98 1995
 
CASE WESTERN RESERVE UNIVERSITY (1)
4,571,292 Apparatus for electrochemical measurements 470 1982
 
OPTISCAN, INC. (1)
5,515,847 Self-emission noninvasive infrared spectrophotometer 170 1994
 
QBC DIAGNOSTICS, INC. (4)
5,635,362 Assay of blood or other biologic samples for target analytes 61 1994
5,834,217 Assay of blood or other biologic samples for target analytes 57 1996
5,759,794 Assay of blood or other biologic samples for target analytes 48 1996
5,776,710 Assay of blood or other biologic samples for target analytes 55 1996
 
LIFESCAN, INC. (62)
4,935,346 Minimum procedure system for the determination of analytes 284 1986
5,049,487 Automated initiation of timing of reflectance readings 476 1988
5,059,394 Analytical device for the automated determination of analytes in fluids 382 1988
5,179,005 Minimum procedure system for the determination of analytes 252 1988
5,306,623 Visual blood glucose concentration test strip 251 1991
5,187,100 Dispersion to limit penetration of aqueous solutions into a membrane 209 1991
5,418,142 Glucose test strip for whole blood 224 1992
5,304,468 Reagent test strip and apparatus for determination of blood glucose 664 1993
5,426,032 No-wipe whole blood glucose test strip 324 1993
5,453,360 Oxidative coupling dye for spectrophotometric quantitive analysis of analytes 164 1994
5,515,170 Analyte detection device having a serpentine passageway for indicator strips 189 1994
5,526,120 Test strip with an asymmetrical end insuring correct insertion for measuring 405 1994
5,563,031 Highly stable oxidative coupling dye for spectrophotometric determination of analytes 171 1994
6,335,203 Optically readable strip for analyte detection having on-strip orientation index 160 1994
5,563,042 Whole blood glucose test strip 249 1995
6,395,227 Test strip for measuring analyte concentration over a broad range of sample volume 138 1995
5,620,863 Blood glucose strip having reduced side reactions 174 1995
5,922,530 Stable coupling dye for photometric determination of analytes 132 1995
5,605,837 Control solution for a blood glucose monitor 185 1996
5,780,304 Method and apparatus for analyte detection having on-strip standard 199 1996
5,843,691 Visually-readable reagent test strip 187 1996
6,168,957 Diagnostic test strip having on-strip calibration 185 1997
5,789,255 Blood glucose strip having reduced sensitivity to hematocrit 168 1997
5,843,692 Automatic initiation of a time interval for measuring glucose concentration in a sample of whole blood 205 1997
5,968,760 Temperature-Independent Blood Glucose Measurement 163 1997
6,284,125 Electrochemical cell 213 1998
6,045,567 Lancing device causing reduced pain 234 1999
6,197,040 Lancing device having a releasable connector 202 1999
6,179,979 Electrochemical cell 151 1999
6,200,773 Diagnostics based on tetrazolium compounds 151 1999
6,174,420 Electrochemical cell 144 1999
6,268,162 Reflectance measurement of analyte concentration with automatic initiation of timing 206 1999
6,193,873 Sample detection to initiate timing of an electrochemical assay 346 1999
6,521,182 Fluidic device for medical diagnostics 166 1999
6,261,519 Medical diagnostic device with enough-sample indicator 179 1999
6,379,513 Sensor connection means 70 1999
6,454,921 Electrochemical cell 49 1999
6,218,571 8-(anilino)-1-naphthalenesulfonate analogs 122 1999
6,475,372 Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations 266 2000
6,485,923 Reagent test strip for analyte determination having hemolyzing agent 141 2000
6,325,917 Method and apparatus for automatic analysis 45 2000
6,571,651 Method of preventing short sampling of a capillary or wicking fill device 176 2000
6,488,827 Capillary flow control in a medical diagnostic device 153 2000
6,592,744 Method of filling an amperometric cell 122 2000
6,444,115 Electrochemical method for measuring chemical reaction rates 198 2000
6,632,349 Hemoglobin sensor 210 2000
6,638,415 Antioxidant sensor 149 2000
6,413,410 Electrochemical cell 236 2000
6,475,360 Heated electrochemical cell 194 2000
6,555,061 Multi-layer reagent test strip 194 2000
6,521,110 Electrochemical cell 218 2000
6,531,322 Visual blood glucose test strip 143 2000
6,558,528 Electrochemical test strip cards that include an integral dessicant 193 2000
6,512,986 Method for automated exception-based quality control compliance for point-of-care devices 128 2000
6,489,133 Apparatus for determinating the concentration of glucose in whole blood 142 2001
6,549,796 Monitoring analyte concentration using minimally invasive devices 370 2001
6,501,976 Percutaneous biological fluid sampling and analyte measurement devices and methods 187 2001
6,576,416 Analyte measurement device and method of use 175 2001
6,491,870 Optically readable strip for analyte detection having on-strip orientation index 135 2001
6,689,411 Solution striping system 150 2001
6,676,995 Solution striping system 168 2002
6,572,822 Visual blood glucose test strip 138 2002
 
MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (6)
4,897,173 Biosensor and method for making the same 491 1987
5,120,420 Biosensor and a process for preparation thereof 708 1989
5,266,179 Quantitative analysis method and its system using a disposable sensor 759 1991
5,192,415 Biosensor utilizing enzyme and a method for producing the same 450 1992
5,658,443 Biosensor and method for producing the same 157 1994
5,948,289 Laser beam machining method 51 1996
 
MATRIA HEALTHCARE, LLC (1)
5,182,707 Apparatus for recording reagent test strip data by comparison to color lights on a reference panel 263 1990
 
YASSINZADEH, ZIA (1)
5,700,695 Sample collection and manipulation method 359 1994
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
ASCENSIA DIABETES CARE HOLDINGS AG (7)
8,401,873 Health data management device 1 2008
8,649,997 Systems and methods for predicting ambient temperature in a fluid analyte meter 1 2009
* 2011/0191,059 Systems and Methods for Predicting Ambient Temperature in a Fluid Analyte Meter 13 2009
8,617,381 System and apparatus for determining temperatures in a fluid analyte system 2 2010
* 2010/0319,436 System and Apparatus for Determining Temperatures in a Fluid Analyte System 13 2010
9,189,598 Fluid analyte meter 0 2013
9,097,650 System and apparatus for determining temperatures in a fluid analyte system 0 2013
 
Other [Check patent profile for assignment information] (1)
9,347,910 Systems and methods for improved stability of electrochemical sensors 0 2015
 
ROCHE DIABETES CARE, INC. (4)
* 2007/0264,721 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT USING A NONLINEAR SAMPLE RESPONSE 97 2007
8,148,164 System and method for determining the concentration of an analyte in a sample fluid 1 2009
8,298,828 System and method for determining the concentration of an analyte in a sample fluid 2 2012
8,586,373 System and method for determining the concentration of an analyte in a sample fluid 0 2012
 
CILAG GMBH INTERNATIONAL (3)
8,551,320 System and method for measuring an analyte in a sample 1 2009
8,932,445 Systems and methods for improved stability of electrochemical sensors 0 2010
8,617,370 Systems and methods of discriminating between a control sample and a test fluid using capacitance 0 2010
 
LIFESCAN SCOTLAND LIMITED (1)
9,243,276 Method and system to determine hematocrit-insensitive glucose values in a fluid sample 0 2013
 
DEXCOM, INC. (1)
9,149,220 Advanced analyte sensor calibration and error detection 0 2012
 
ROCHE OPERATIONS LTD. (5)
* 7,981,363 System and method for analyte measurement 11 2008
* 2008/0098,802 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT 104 2008
* 2011/0236,963 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT 0 2011
* 8,691,152 System and method for analyte measurement 0 2012
* 2012/0135,508 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT 17 2012
 
LIFESCAN, INC. (17)
8,529,751 Systems and methods for discriminating control solution from a physiological sample 0 2006
* 2007/0235,347 Systems and Methods for Discriminating Control Solution from a Physiological Sample 111 2006
8,778,168 Systems and methods of discriminating control solution from a physiological sample 0 2008
* 2009/0084,687 SYSTEMS AND METHODS OF DISCRIMINATING CONTROL SOLUTION FROM A PHYSIOLOGICAL SAMPLE 111 2008
8,603,768 System and method for measuring an analyte in a sample 0 2009
8,486,649 System and method for measuring an analyte in a sample 0 2009
8,877,034 Systems, devices, and methods for measuring whole blood hematocrit based on initial fill velocity 0 2009
8,101,065 Systems, devices, and methods for improving accuracy of biosensors using fill time 5 2009
* 2011/0155,585 Systems, Devices, and Methods for Improving Accuracy of Biosensors Using Fill Time 8 2009
* 2011/0155,584 Systems, Devices, and Methods for Measuring Whole Blood Hematocrit Based on Initial Fill Velocity 6 2009
8,449,740 Systems and methods for discriminating control solution from a physiological sample 0 2010
* 2011/0011,752 SYSTEMS AND METHODS FOR DISCRIMINATING CONTORL SOLUTION FROM A PHYSIOLOGICAL SAMPLE 11 2010
8,623,198 Systems, devices, and methods for improving accuracy of biosensors using fill time 2 2010
9,157,110 Systems and methods of discriminating control solution from a physiological sample 0 2012
8,916,040 System and method for measuring an analyte in a sample 0 2012
8,709,739 System and method for measuring an analyte in a sample 0 2012
9,274,078 Systems and methods of discriminating control solution from a physiological sample 0 2013
* Cited By Examiner

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