System and method for analyte measurement using AC phase angle measurements

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7390667
APP PUB NO 20040157337A1
SERIAL NO

10688312

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddressTotal Patents
ROCHE DIABETES CARE, INC.INDIANAPOLIS, IN, US1119
ROCHE OPERATIONS LTD.HAMILTON62

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beaty, Terry A Indianapolis, IN 28 1574
Burke, David W Carmel, IN 48 3322
Kuhn, Lance S Fishers, IN 20 2036
Svetnik, Vladimir Morristown, NJ 16 2241

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (7)
4413628 pH Monitor electrode electrolyte cartridge 42 1980
4431004 Implantable glucose sensor 775 1981
5312762 Method of measuring an analyte by measuring electrical resistance of a polymer film reacting with the analyte 151 1991
5376254 Potentiometric electrochemical device for qualitative and quantitative analysis 39 1993
6121050 Analyte detection systems 65 1997
6246330 Elimination-absorber monitoring system 260 1998
6176988 Membrane electrode for measuring the glucose concentration in fluids 53 1998
 
WALES ABERYSTWYTH, UNIVERSITY OF (1)
5569591 Analytical or monitoring apparatus and method 159 1994
 
ALUSUISSE LONZA GROUP, AG (1)
5500350 Binding assay device 110 1994
 
Solid State Farms, Inc. (2)
5508203 Apparatus and method for radio frequency spectroscopy using spectral analysis 236 1993
5792668 Radio frequency spectral analysis for in-vitro or in-vivo environments 218 1996
 
Calypte, Inc. (1)
5447837 Multi-immunoassay diagnostic system for antigens or antibodies or both 70 1989
 
INTERNATIONAL TECHNIDYNE CORPORATION (1)
5504011 Portable test apparatus and associated method of performing a blood coagulation test 99 1994
 
ENDRESS + HAUSER GMBH + CO. KG (1)
6389891 Method and apparatus for establishing and/or monitoring the filling level of a medium in a container 54 2000
 
MIT Development Corporation (1)
6201607 Blood fluid characteristics analysis instrument 56 1999
 
TERUMO KABUSHIKI KAISHA (1)
4927516 Enzyme sensor 548 1987
 
RELIA BIOTECHNOLOGIES (SHENZHEN) LTD. (1)
6136610 Method and apparatus for performing a lateral flow assay 117 1998
 
DUQUESNE UNIVERSITY OF THE HOLY GHOST (1)
5469846 Implantable non-enzymatic electrochemical glucose sensor 503 1994
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (2)
5965380 Subcutaneous glucose electrode 998 1999
6121009 Electrochemical analyte measurement system 977 1999
 
ELI LILLY AND COMPANY (1)
5786584 Vial and cartridge reading device providing audio feedback for a blood glucose monitoring system 255 1996
 
ELAN PHARMA INTERNATIONAL LIMITED (1)
5820622 Analyte-controlled liquid delivery device and analyte monitor 561 1996
 
HUGHES ELECTRONICS CORPORATION (1)
5018164 Excimer laser ablation method and apparatus for microcircuit fabrication 65 1989
 
Moorlodge Ventures Limited (1)
6660141 Electrochemical sensor 17 2001
 
TECHNICAL CHEMICALS & PRODUCTS (1)
6574425 Reflectometer 77 1998
 
ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (1)
6259937 Implantable substrate sensor 692 1998
 
SIMCAH PARTNERS, L.P. (1)
* 5232667 Temperature control for portable diagnostic system using a non-contact temperature probe 63 1992
 
ANIMAS TECHNOLOGIES, LLC (5)
6180416 Method and device for predicting physiological values 449 1998
6144869 Monitoring of physiological analytes 557 1999
6272364 Method and device for predicting physiological values 600 1999
6326160 Microprocessors for use in a device for predicting physiological values 513 1999
6594514 Device for monitoring of physiological analytes 275 2001
 
Evreka, Inc. (1)
4436094 Monitor for continuous in vivo measurement of glucose concentration 533 1982
 
E. HELLER & CO. (4)
6134461 Electrochemical analyte 1185 1998
6175752 Analyte monitoring device and methods of use 1537 1998
6484046 Electrochemical analyte sensor 978 2000
6565509 Analyte monitoring device and methods of use 1094 2000
 
Tall Oak Ventures (1)
6153069 Apparatus for amperometric Diagnostic analysis 424 1995
 
EG&G OCEAN PRODUCTS, INC. (1)
4652830 Analyzer for comparative measurements of bulk conductivity 46 1985
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (3)
4671288 Electrochemical cell sensor for continuous short-term use in tissues and blood 950 1985
4703756 Complete glucose monitoring system with an implantable, telemetered sensor module 1028 1986
5650061 Large amplitude sinusoidal voltammetry 59 1995
 
HEALTH HERO NETWORK, INC. (1)
6168563 Remote health monitoring and maintenance system 853 1999
 
X-RITE, INCORPORATED (1)
5118183 Automated strip reader densitometer 68 1990
 
E. I. DU PONT DE NEMOURS AND COMPANY (1)
4832814 Electrofusion cell and method of making the same 75 1987
 
CASCADE ENGINEERING, INC. (1)
6206282 RF embedded identification device 192 1999
 
ACTIMED LABORATORIES, INC. (1)
5234813 Method and device for metering of fluid samples and detection of analytes therein 132 1991
 
THE CLEVELAND CLINIC FOUNDATION (1)
4897162 Pulse voltammetry 368 1988
 
NATIONAL SCIENCE COUNCIL (1)
6042714 Method and chemical sensor for determining concentrations of hydrogen peroxide and its precursor in a liquid 58 1997
 
UNIVERSITY OF WASHINGTON (1)
6277641 Methods for analyzing the presence and concentration of multiple analytes using a diffusion-based chemical sensor 71 1999
 
Phase Dynamics, Inc. (1)
* 5748002 RF probe for montoring composition of substances 48 1996
 
DELSYS PHARMACEUTICAL CORPORATION (1)
6287595 Biomedical assay device 69 2000
 
BRITISH TECHNOLOGY GROUP LIMITED (1)
5691633 Method of and apparatus for determining a property of a sample 44 1995
 
NEXGEN MICROSYSTEMS, INC. (1)
5572159 Voltage-controlled delay element with programmable delay 66 1994
 
PROVENANCE ASSET GROUP LLC (1)
6295506 Measurement apparatus 670 1998
 
KUMETRIX, INC. (1)
5801057 Microsampling device and method of construction 433 1996
 
PROVALIS DIAGNOSTICS LIMITED (1)
6300142 Device and apparatus for conducting an assay 82 2000
 
ABBOTT LABORATORIES (2)
6540891 Test strip 386 2001
6600997 Analyte test instrument having improved calibration and communication processes 184 2001
 
GB BIOSCIENCES CORPORATION (1)
5654178 Immunoassay for tetrachloroisophthalonitrile (chlorothalonil), its derivatives and breakdown products 39 1995
 
STAT MEDICAL DEVICES, INC. (1)
6156051 Lancet having adjustable penetration depth 359 1999
 
SENSOR DIAGNOSTICS, INC. (1)
4713347 Measurement of ligand/anti-ligand interactions using bulk conductance 218 1985
 
ICU MEDICAL, INC. (1)
* 5261411 Thermal drift correction while continuously monitoring cardiac output 79 1991
 
LighTouch Medical, Inc. (1)
6044285 Method for non-invasive measurement of an analyte 145 1998
 
Hybrivet Systems, Inc. (1)
5039618 Test swab cartridge type device and method for detecting lead and cadmium 60 1990
 
GEMALTO SA (1)
6206292 Surface-printable RFID-transponders 188 2000
 
METRIKA LABORATORIES, INC. (2)
5580794 Disposable electronic assay device 390 1995
5837546 Electronic assay device and method 390 1996
 
PHARMACONTROL CORPORATION (1)
4750496 Method and apparatus for measuring blood glucose concentration 412 1987
 
ABBOTT DIABETES CARE INC. (25)
6071391 Enzyme electrode structure 609 1997
6251260 Potentiometric sensors for analytic determination 427 1998
6281006 Electrochemical affinity assay 394 1998
6638716 Rapid amperometric verification of PCR amplification of DNA 77 1998
6294281 Biological fuel cell and method 320 1998
6143164 Small volume in vitro analyte sensor 1032 1998
6338790 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 679 1999
6299757 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 629 1999
6461496 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 865 1999
6616819 Small volume in vitro analyte sensor and methods 667 1999
6156173 Enzyme electrode structure 115 2000
6551494 Small volume in vitro analyte sensor 626 2000
6592745 Method of using a small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 587 2000
6618934 Method of manufacturing small volume in vitro analyte sensor 876 2000
6654625 Mass transport limited in vivo analyte sensor 846 2000
6591125 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 994 2000
6579690 Blood analyte monitoring through subcutaneous measurement 1007 2000
6503381 Biosensor 490 2000
6329161 Subcutaneous glucose electrode 1048 2000
6605200 Polymeric transition metal complexes and uses thereof 595 2000
6605201 Transition metal complexes with bidentate ligand having an imidazole ring and sensor constructed therewith 596 2000
6607658 Integrated lancing and measurement device and analyte measuring methods 567 2000
6560471 Analyte monitoring device and methods of use 1025 2001
6623501 Reusable ceramic skin-piercing device 498 2001
6531239 Biological fuel cell and methods 77 2001
 
INVERNESS MEDICAL TECHNOLOGY, INC. (3)
5708247 Disposable glucose test strips, and methods and compositions for making same 669 1996
5951836 Disposable glucose test strip and method and compositions for making same 470 1998
6241862 Disposable test strips with integrated reagent/blood separation layer 458 1999
 
INVERNESS MEDICAL SWITZERLAND GMBH (1)
5141868 Device for use in chemical test procedures 682 1989
 
KYOTO DAIICHI KAGAKU CO., LTD. (3)
5720862 Sensor and production method of and measurement method using the same 410 1996
6377896 Method and apparatus for determination of a substance coexisting with another substance 55 1999
6349230 Blood measuring instrument 64 2000
 
KROHNE MESSTECHNIK GMBH (1)
6401532 Fill level gauge 42 2001
 
BOEHRINGER, A CORP. OF GERMANY (1)
4510383 Device for the optical identification of a coding on a diagnostic test strip 75 1982
 
PANASONIC HEALTHCARE CO., LTD. (1)
6599406 Concentration measuring apparatus, test strip for the concentration measuring apparatus, biosensor system and method for forming terminal on the test strip 170 2000
 
Seiko Instruments & Electronics Ltd. (1)
4789804 Analytical device and method utilizing a piezoelectric crystal biosensor 141 1986
 
Visionary Medical Products, Inc. (3)
5728074 Pen-type injector with a microprocessor and blood characteristic monitor 335 1994
5593390 Medication delivery device with a microprocessor and characteristic monitor 549 1995
5925021 Medication delivery device with a microprocessor and characteristic monitor 803 1997
 
OSMETECH TECHNOLOGY INC. (1)
6013170 Detection of analytes using reorganization energy 134 1998
 
ROCHE DIABETES CARE, INC. (31)
4731726 Patient-operated glucose monitor and diabetes management system 1321 1986
4797256 Registration device for blood test strips 86 1987
5053199 Electronically readable information carrier 180 1989
5128015 Method and apparatus for amperometric diagnostic analysis 324 1989
4963814 Regulated bifurcated power supply 62 1989
4999582 Biosensor electrode excitation circuit 236 1989
4999632 Analog to digital conversion with noise reduction 85 1989
5243516 Biosensing instrument and method 169 1989
5232668 Test strip holding and reading mechanism for a meter 142 1991
5246858 Apparatus and method for analyzing a body fluid 78 1991
5108564 Method and apparatus for amperometric diagnostic analysis 523 1991
5371687 Glucose test data acquisition and management system 581 1992
5284770 Meter verification method and apparatus 43 1993
5385846 Biosensor and method for hematocrit determination 182 1993
5352351 Biosensing meter with fail/safe procedures to prevent erroneous indications 601 1993
5405511 Biosensing meter with ambient temperature estimation method and system 251 1993
5413690 Potentiometric biosensor and the method of its use 367 1993
5379214 Method for reading the concentration of a medically significant component of a biological fluid from a test strip 89 1993
5437999 Electrochemical sensor 732 1994
5594906 Zero power receive detector for serial data interface 206 1994
5438271 Biosensing meter which detects proper electrode engagement and distinguishes sample and check strips 396 1994
5762770 Electrochemical biosensor test strip 364 1995
6162639 Embossed test strip system 240 1998
6413395 Biosensor apparatus 54 1999
6627057 Microsphere containing sensor 52 1999
6413213 Subscription based monitoring system and method 65 2000
6645359 Biosensor 96 2000
6540890 Biosensor 68 2000
6447657 Biosensor 83 2000
6544474 Device for determination of an analyte in a body fluid using small sample sizes 62 2001
* 7018843 Instrument 73 2001
 
MILES INC. (4)
4938860 Electrode for electrochemical sensors 385 1985
4806311 Multizone analytical element having labeled reagent concentration zone 175 1985
4806312 Multizone analytical element having detectable signal concentrating zone 130 1985
5250439 Use of conductive sensors in diagnostic assays 437 1992
 
INVERNESS MEDICAL - BIOSTAR INC. (1)
5639671 Methods for optimizing of an optical assay device 95 1995
 
NOVO NORDISK A/S (1)
5269891 Method and apparatus for determination of a constituent in a fluid 493 1993
 
AMP Incorporated (1)
4648665 Electronic key assemblies 48 1985
 
TRIVIDIA HEALTH, INC. (5)
5296192 Diagnostic test strip 84 1992
6525330 Method of strip insertion detection 88 2001
6541266 Method for determining concentration of an analyte in a test strip 283 2001
6562625 Distinguishing test types through spectral analysis 77 2001
6743635 System and methods for blood glucose sensing 497 2002
 
QUEEN MARY & WESTFIELD COLLEGE (1)
6300123 Sensor employing impedance measurements 51 1999
 
BECTON, DICKINSON AND COMPANY (2)
4628193 Code reading operations supervisor 153 1980
4703017 Solid phase assay with visual readout 334 1984
 
DADE BEHRING INC. (1)
4517291 Biological detection process using polymer-coated electrodes 101 1983
 
NANOGEN, INC. (1)
5605662 Active programmable electronic devices for molecular biological analysis and diagnostics 779 1993
 
CYTYC CORPORATION (1)
6394952 Point of care diagnostic systems 163 1998
 
3M INNOVATIVE PROPERTIES COMPANY (2)
6203952 Imaged article on polymeric substrate 117 1999
6399258 Method for patterning thin films 53 2001
 
AFFYMETRIX, INC. (1)
5922591 Integrated nucleic acid diagnostic device 679 1996
 
TECAN TRADING AG (1)
6143247 Affinity binding-based system for detecting particulates in a fluid 222 1997
 
PACKARD INSTRUMENT COMPANY, INC. (1)
6538735 Method and apparatus for producing and measuring light and for determining the amounts of analytes in microplate wells 44 2000
 
CONMED CORPORATION (1)
5921925 Biomedical electrode having a disposable electrode and a reusable leadwire adapter that interfaces with a standard leadwire connector 100 1997
 
Houston Advanced Research Center (1)
5532128 Multi-site detection apparatus 226 1994
 
NIPRO DIAGNOSTICS, INC. (1)
6284550 Diagnostic sanitary test strip 79 1999
 
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (1)
5611900 Microbiosensor used in-situ 405 1995
 
LIFECAN, INC. (1)
6420128 Test strips for detecting the presence of a reduced cofactor in a sample and method for using the same 158 2000
 
ELECTROSYNTHESIS COMPANY (1)
5437772 Portable lead detector 70 1993
 
DERMAL DEVICES INC. (1)
5890489 Method for non-invasive determination of glucose in body fluids 82 1996
 
DR. HOLGER KIESEWETTER (1)
4547735 Instrument for measuring the hematocrit value of blood 67 1983
 
INVERNESS MEDICAL TECHNOLOGY (1)
5989917 Glucose monitor and test strip containers for use in same 149 1996
 
BOEHRINGER MANNHEIM GMBH (19)
4477575 Process and composition for separating plasma or serum from whole blood 282 1981
4476149 Process for the production of an analysis test strip 95 1982
4592893 Analysis test strip 109 1984
4578716 Method of and apparatus for making a test strip and a test strip made by such method 60 1984
4676653 Apparatus for determining the diffuse reflectivity of a sample surface of small dimensions 84 1984
4816224 Device for separating plasma or serum from whole blood and analyzing the same 159 1987
4834234 Container for test strips 97 1988
5035862 Analytical system for the determination of a component of a fluid 51 1988
5413764 Test carrier analysis system 60 1990
5143694 Test strip evaluating instrument for multiple test strips 72 1990
5122244 Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor 232 1991
5281395 Test carrier analysis system 228 1991
5286362 Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor 498 1993
5424035 Test strip analysis system 152 1994
5489414 System for analyzing compounds contained in liquid samples 262 1994
5556789 Device for the simultaneous determination of several analytes 55 1994
5445967 Method for analyzing a component of a liquid sample 70 1994
5645798 Test elements in sealed chambers for analyzing compounds contained in liquid samples 99 1995
5757666 System for analyzing compounds contained liquid samples 100 1996
 
LONZA GROUP AG (1)
5604110 Binding assay device 61 1995
 
MEDISENSE, INC. (7)
4545382 Sensor for components of a liquid mixture 787 1982
4711245 Sensor for components of a liquid mixture 710 1984
5509410 Strip electrode including screen printing of a single layer 760 1994
5682884 Strip electrode with screen printing 528 1994
5727548 Strip electrode with screen printing 461 1995
5628890 Electrochemical sensor 972 1995
5849174 Electrodes and their use in analysis 226 1997
 
OttoSensors Corporation (1)
4682602 Probe for medical application 312 1985
 
LRE Technology Partner GmbH (3)
5904898 Test strip 76 1998
6315951 Test strip measuring system 56 1999
6525549 Method for determining the concentration of a substance in a liquid by measuring electrical current in a test strip 60 2000
 
PANASONIC CORPORATION (1)
5264103 Biosensor and a method for measuring a concentration of a substrate in a sample 672 1992
 
QUESTSTAR MEDICAL, INC. (1)
5279294 Medical diagnostic system 848 1990
 
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (1)
5670031 Electrochemical sensor 360 1995
 
FA. LPKF CAD/CAM SYSTEME GMBH (1)
5576073 Method for patterned metallization of a substrate surface 68 1995
 
ACUSON CORPORATION (1)
6300961 Ultrasonic system and method for processing data 41 1999
 
SMITHKLINE DIAGNOSTICS, INC. (1)
4935106 Ion selective/enzymatic electrode medical analyzer device and method of use 53 1985
 
EURUS LLC (1)
5019974 Diabetes management system and apparatus 886 1990
 
HITACHI, LTD. (1)
5470533 Test strip supply apparatus and analyzer using same 52 1993
 
UMM Electronics, Inc. (1)
6150124 Method for passively determining the application of a sample fluid on an analyte strip 53 1999
 
LPKF LASER & ELECTRONICS AG (1)
5593739 Method of patterned metallization of substrate surfaces 58 1996
 
CUMMINS FILTRATION INC. (1)
2004/0094,459 LIQUID FILTER WITH SEPARATE AND CALIBRATED VAPOR RELEASE 2 2003
 
DISETRONIC LICENSING AG (2)
5411647 Techniques to improve the performance of electrochemical sensors 916 1994
5695623 Glucose measuring device 632 1994
 
MARCONI COMMUNICATIONS LIMITED (1)
6576461 Electrochemical affinity assay 68 2001
 
I-STAT CORPORATION (3)
5096669 Disposable sensing device for real time fluid analysis 530 1988
4954087 Static-free interrogating connector for electric components 83 1990
5112455 Method for analytically utilizing microfabricated sensors during wet-up 220 1990
 
CLINICAL DIAGNOSTIC SYSTEMS (4)
4323536 Multi-analyte test device 141 1980
4413407 Method for forming an electrode-containing device with capillary transport between electrodes 86 1981
4552458 Compact reflectometer 121 1983
5126952 Bar coding calibration 40 1991
 
FIRST NATIONAL BANK OF BOSTON, THE (2)
4686479 Apparatus and control kit for analyzing blood sample values including hematocrit 95 1985
4759828 Glucose electrode and method of determining glucose 569 1987
 
Optikos Corporation (1)
6226081 Optical height of fill detection system and associated methods 59 1998
 
MAGELLAN DIAGNOSTICS, INC. (1)
6391558 Electrochemical detection of nucleic acid sequences 109 2000
 
CIBA CORNING DIAGNOSTICS CORP. (2)
5066372 Unitary multiple electrode sensor 90 1990
5421189 Electrical connection system for electrochemical sensors 54 1994
 
CORANGE INTERNATIONAL LIMITED (UNDIVIDED 1/2 INTEREST) (1)
5366609 Biosensing meter with pluggable memory key 516 1993
 
Hygeia Sciences, Inc. (1)
5141850 Porous strip form assay device method 219 1990
 
Asulab S.A. (1)
5395504 Electrochemical measuring system with multizone sensors 467 1994
 
SIEMENS AKTIENGESELLSCHAFT (2)
4477314 Method for determining sugar concentration 417 1983
4919770 Method for determining the concentration of electro-chemically convertible substances 169 1986
 
ABBOTT LABORATORIES (9)
5075077 Test card for performing assays 190 1988
5311426 Apparatus and method for providing assay calibration data 94 1992
5635364 Assay verification control for an automated analytical system 98 1994
5820551 Strip electrode with screen printing 554 1995
6129823 Low volume electrochemical sensor 341 1997
6087182 Reagentless analysis of biological samples 102 1998
6565738 Diagnostic test for the measurement of analyte in abiological fluid 95 1999
6377894 Analyte test instrument having improved calibration and communication processes 310 1999
6526298 Method for the non-invasive determination of analytes in a selected volume of tissue 348 2000
 
INSTITUT FUR CHEMO-UND BIOSENSORIK MUNSTER E.V. (1)
* 6004442 Analyte-selective sensor 88 1997
 
GENZYME CORPORATION (1)
5656502 Test strip holder and method of use 104 1995
 
PBI TECHNOLOGY, INC. (1)
6102872 Glucose detector and method 87 1998
 
LIFESCAN, IC., A CORP. OF CA. (1)
4976724 Lancet ejector mechanism 318 1989
 
Microcor, Inc. (2)
5526808 Method and apparatus for noninvasively determining hematocrit 93 1995
5642734 Method and apparatus for noninvasively determining hematocrit 118 1996
 
CAMBRIDGE LIFE SCIENCES PLC (2)
4970145 Immobilized enzyme electrodes 441 1988
5846744 Sensors based on polymer transformation 263 1996
 
Biologix, Inc. (2)
4940945 Interface circuit for use in a portable blood chemistry measuring apparatus 74 1987
* 4929426 Portable blood chemistry measuring apparatus 172 1988
 
FUJI ELECTRIC CO., LTD. (1)
4407959 Blood sugar analyzing apparatus 267 1981
 
BAYER HEALTHCARE LLC (2)
5630986 Dispensing instrument for fluid monitoring sensors 370 1995
5653863 Method for reducing bias in amperometric sensors 605 1996
 
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (2)
4805624 Low-potential electrochemical redox sensors 416 1987
6271044 Method and kit for detecting an analyte 50 1998
 
DRAGERWERK AKTIENGESELLSCHAFT (1)
4499423 Circuit arrangement for correction of a sensor output 42 1981
 
ASSURANCE BIOTECH LLC (1)
6514769 Multiple analyte assay device with sample integrity monitoring system 80 1999
 
BAYER AKTIENGESELLSCHAFT (1)
5916156 Electrochemical sensors having improved selectivity and enhanced sensitivity 206 1997
 
SHIMADZU CORPORATION (1)
4820399 Enzyme electrodes 491 1985
 
Cardiac Pacemakers, Inc. (1)
4679562 Glucose sensor 345 1986
 
University Patents, Inc. (1)
4440175 Membrane electrode for non-ionic species 302 1981
 
TECHNIMED CORPORATION (1)
4877580 Assay kit including an analyte test strip and a color comparator 88 1988
 
Migrata U.K. Ltd. (1)
4654197 Cuvette for sampling and analysis 412 1984
 
NIPPON TELEGRAPH AND TELEPHONE CORPORATION (1)
5389215 Electrochemical detection method and apparatus therefor 93 1993
 
LXN Corporation (1)
5885839 Methods of determining initiation and variable end points for measuring a chemical reaction 62 1997
 
BAYER CORPORATION (9)
5552116 Test strip pick-up mechanism in automated analyzer 48 1995
5620579 Apparatus for reduction of bias in amperometric sensors 299 1995
5665215 Method and apparatus for making predetermined events with a biosensor 95 1995
5723284 Control solution and method for testing the performance of an electrochemical device for determining the concentration of an analyte in blood 237 1996
5883378 Apparatus and methods for transmitting electrical signals indicative of optical interactions between a light beam and a flowing suspension of particles 92 1996
5856195 Method and apparatus for calibrating a sensor element 227 1996
5798031 Electrochemical biosensor 396 1997
6391645 Method and apparatus for correcting ambient temperature effect in biosensors 85 1997
6246966 Method and apparatus for data management authentication in a clinical analyzer 59 1998
 
IMPERIAL CHEMICAL INDUSTRIES PLC (1)
4935105 Methods of operating enzyme electrode sensors 334 1989
 
GENETICS INTERNATIONAL, INC. (1)
4820636 Electrochemical assay for cis-diols 73 1986
 
PANASONIC HEALTHCARE HOLDINGS CO., LTD. (11)
5582697 Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same 686 1995
5575895 Biosensor and method for producing the same 464 1995
5650062 Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same 473 1995
6004441 Biosensor 340 1997
6225078 Method for quantitative measurement of a substrate 192 1998
6258254 Biosensor 194 1998
6656702 Biosensor containing glucose dehydrogenase 204 1999
RE36991 Biosensor and method for producing the same 215 1999
6309526 Biosensor 227 1999
6340428 Device and method for determining the concentration of a substrate 78 1999
6342364 Cholesterol sensor and method of determining cholesterol 46 2001
 
BECKMAN COULTER, INC. (3)
5344754 Assay timed by electrical resistance change and test strip 81 1993
5554531 Device for performing timed assay by electrical resistance change 80 1995
6061128 Verification device for optical clinical assay systems 188 1998
 
RUBICON INVESTMENTS, INC. (1)
6128519 System and method for measuring a bioanalyte such as lactate 90 1998
 
THERASENSE, INC. (5)
6103033 Process for producing an electrochemical biosensor 1156 1998
6120676 Method of using a small volume in vitro analyte sensor 1150 1999
6576101 Small volume in vitro analyte sensor 641 1999
6162611 Subcutaneous glucose electrode 988 2000
6514718 Subcutaneous glucose electrode 815 2001
 
ALZA CORPORATION (1)
6091975 Minimally invasive detecting device 809 1998
 
ORASURE TECHNOLOGIES, INC. (1)
5112758 Treating body fluids for diagnostic testing 48 1988
 
Sensors for Medicine and Science, Inc. (1)
6330464 Optical-based sensing devices 525 1999
 
ESA BIOSCIENCES, INC. (1)
5873990 Handheld electromonitor device 203 1996
 
Spectrum Systems, Inc. (1)
5508200 Method and apparatus for conducting multiple chemical assays 259 1992
 
ARKRAY, INC. (2)
6180062 Device for analyzing a sample 59 1999
6576117 Method and apparatus for electrochemical measurement using statistical technique 403 2001
 
Thomson-CSF (1)
4420564 Blood sugar analyzer having fixed enzyme membrane sensor 409 1981
 
CALIFORNIA INSTITUTE OF TECHNOLOGY (3)
5788833 Sensors for detecting analytes in fluids 124 1996
5911872 Sensors for detecting analytes in fluids 118 1997
6170318 Methods of use for sensor based fluid detection devices 243 1998
 
MEDTRONIC CRYOCATH LP (1)
5232516 Thermoelectric device with recuperative heat exchangers 175 1991
 
SIEMENS MEDICAL SOLUTIONS USA, INC. (2)
5971923 Ultrasound system and method for interfacing with peripherals 89 1997
6262749 Ultrasonic system and method for data transfer, storage and/or processing 58 1997
 
HYPOGUARD LIMITED (1)
5494638 Support membrane 60 1994
 
AT&T LABS, INC. (1)
5353351 Secure teleconferencing 79 1992
 
JPMORGAN CHASE BANK, N.A. (1)
5597532 Apparatus for determining substances contained in a body fluid 156 1994
 
RIGAKU CORPORATION (1)
6570390 Method for measuring surface leakage current of sample 36 2001
 
Mallinckrodt Sensor Systems, Inc. (1)
4734184 Self-activating hydratable solid-state electrode apparatus 134 1987
 
Hosiden Electronics Co., Ltd. (1)
4810203 Electrical connector 59 1987
 
NOVA BIOMEDICAL CORPORATION (3)
4975647 Controlling machine operation with respect to consumable accessory units 206 1988
6258229 Disposable sub-microliter volume sensor and method of making 298 1999
6287451 Disposable sensor and method of making 187 1999
 
SYVA COMPANY (1)
5439826 Method of distinguishing among strips for different assays in an automated instrument 70 1988
 
ROCHE OPERATIONS LTD. (3)
5997817 Electrochemical biosensor test strip 495 1997
6270637 Electrochemical biosensor test strip 324 1999
6645368 Meter and method of using the meter for determining the concentration of a component of a fluid 272 2000
 
ROCHE DIAGNOSTICS CORPORATION (3)
4642295 Methods of determining fructosamine levels in blood samples 58 1982
5288636 Enzyme electrode system 583 1990
5508171 Assay method with enzyme electrode system 536 1994
 
GENERAL ELECTRIC COMPANY (1)
4865873 Electroless deposition employing laser-patterned masking layer 83 1987
 
MOLECULAR DEVICES CORPORATION (2)
4849330 Photoresponsive redox detection and discrimination 83 1985
4956275 Migratory detection immunoassay 113 1987
 
MILES LABORATORIES, INC. (1)
4714874 Test strip identification and instrument calibration 209 1985
 
The BOC Group, Inc. (1)
4407290 Blood constituent measuring device and method 319 1981
 
ROCHE DIAGNOSTICS OPERATIONS, INC. (4)
5526111 Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control 52 1993
5686659 Fluid dose flow and coagulation sensor for medical instrument 66 1995
5710622 Fluid dose, flow and coagulation sensor for medical instrument 39 1995
5832921 Analog heater control for medical instrument 43 1995
 
ST. JUDE MEDICAL, INC. (1)
4795542 Electrochemical concentration detector device 155 1986
 
RHEONIX, INC. (1)
6358752 Liposome-enhanced test device and method 64 1999
 
Ortho Pharmaceutical Corporation (1)
5179288 Apparatus and method for measuring a bodily constituent 68 1991
 
SEGARS CALIFORNIA PARTNERS, LP (1)
5220920 Electrochemical measurement system having interference reduction circuit 87 1991
 
MicroFab Technologies, Inc. (1)
5658802 Method and apparatus for making miniaturized diagnostic arrays 233 1995
 
APEX BIOTECHNOLOGY CORP. (1)
6491803 Test strip and biosensor incorporating with nanometer metal particles 77 2001
 
Innovative Biotechnologies, Inc. (1)
6159745 Interdigitated electrode arrays for liposome-enhanced immunoassay and test device 55 1999
 
WAVESENSE, INC. (1)
6136549 systems and methods for performing magnetic chromatography assays 106 1999
 
SIEMENS HEALTHCARE DIAGNOSTICS INC. (7)
5477326 Spectrophotometer arrangement with multi-detector readhead 65 1994
5569608 Quantitative detection of analytes on immunochromatographic strips 149 1995
5691486 Apparatus and methods for selecting a variable number of test sample aliquots to mix with respective reagents 63 1996
5719667 Apparatus for filtering a laser beam in an analytical instrument 90 1996
5745308 Methods and apparatus for an optical illuminator assembly and its alignment 103 1996
5945341 System for the optical identification of coding on a diagnostic test strip 104 1996
6316264 Test strip for the assay of an analyte in a liquid sample 62 1999
 
Silver Lake Corporation (1)
6287875 Internally referenced competitive assays 45 2000
 
Keith & Rumph Inventors, Inc. (1)
6126609 Apparatus for taking blood samples from a patient 34 1998
 
LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (1)
5698083 Chemiresistor urea sensor 126 1995
 
CASE WESTERN RESERVE UNIVERSITY (1)
4571292 Apparatus for electrochemical measurements 530 1982
 
OPTISCAN, INC. (1)
5515847 Self-emission noninvasive infrared spectrophotometer 194 1994
 
QBC DIAGNOSTICS, INC. (4)
5635362 Assay of blood or other biologic samples for target analytes 70 1994
5834217 Assay of blood or other biologic samples for target analytes 70 1996
5759794 Assay of blood or other biologic samples for target analytes 52 1996
5776710 Assay of blood or other biologic samples for target analytes 68 1996
 
LIFESCAN, INC. (62)
4935346 Minimum procedure system for the determination of analytes 313 1986
5049487 Automated initiation of timing of reflectance readings 520 1988
5059394 Analytical device for the automated determination of analytes in fluids 412 1988
5179005 Minimum procedure system for the determination of analytes 277 1988
5306623 Visual blood glucose concentration test strip 280 1991
5187100 Dispersion to limit penetration of aqueous solutions into a membrane 219 1991
5418142 Glucose test strip for whole blood 247 1992
5304468 Reagent test strip and apparatus for determination of blood glucose 727 1993
5426032 No-wipe whole blood glucose test strip 355 1993
5453360 Oxidative coupling dye for spectrophotometric quantitive analysis of analytes 182 1994
5515170 Analyte detection device having a serpentine passageway for indicator strips 209 1994
5526120 Test strip with an asymmetrical end insuring correct insertion for measuring 443 1994
5563031 Highly stable oxidative coupling dye for spectrophotometric determination of analytes 191 1994
6335203 Optically readable strip for analyte detection having on-strip orientation index 179 1994
5563042 Whole blood glucose test strip 272 1995
6395227 Test strip for measuring analyte concentration over a broad range of sample volume 158 1995
5620863 Blood glucose strip having reduced side reactions 194 1995
5922530 Stable coupling dye for photometric determination of analytes 150 1995
5605837 Control solution for a blood glucose monitor 204 1996
5780304 Method and apparatus for analyte detection having on-strip standard 220 1996
5843691 Visually-readable reagent test strip 212 1996
6168957 Diagnostic test strip having on-strip calibration 212 1997
5789255 Blood glucose strip having reduced sensitivity to hematocrit 188 1997
5843692 Automatic initiation of a time interval for measuring glucose concentration in a sample of whole blood 229 1997
5968760 Temperature-Independent Blood Glucose Measurement 187 1997
6284125 Electrochemical cell 243 1998
6045567 Lancing device causing reduced pain 264 1999
6197040 Lancing device having a releasable connector 225 1999
6179979 Electrochemical cell 170 1999
6200773 Diagnostics based on tetrazolium compounds 169 1999
6174420 Electrochemical cell 151 1999
6268162 Reflectance measurement of analyte concentration with automatic initiation of timing 234 1999
6193873 Sample detection to initiate timing of an electrochemical assay 403 1999
6521182 Fluidic device for medical diagnostics 190 1999
6261519 Medical diagnostic device with enough-sample indicator 203 1999
6379513 Sensor connection means 79 1999
6454921 Electrochemical cell 53 1999
6218571 8-(anilino)-1-naphthalenesulfonate analogs 140 1999
6475372 Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations 320 2000
6485923 Reagent test strip for analyte determination having hemolyzing agent 160 2000
6325917 Method and apparatus for automatic analysis 47 2000
6571651 Method of preventing short sampling of a capillary or wicking fill device 195 2000
6488827 Capillary flow control in a medical diagnostic device 173 2000
6592744 Method of filling an amperometric cell 140 2000
6444115 Electrochemical method for measuring chemical reaction rates 221 2000
6632349 Hemoglobin sensor 233 2000
6638415 Antioxidant sensor 169 2000
6413410 Electrochemical cell 272 2000
6475360 Heated electrochemical cell 214 2000
6555061 Multi-layer reagent test strip 220 2000
6521110 Electrochemical cell 241 2000
6531322 Visual blood glucose test strip 164 2000
6558528 Electrochemical test strip cards that include an integral dessicant 212 2000
6512986 Method for automated exception-based quality control compliance for point-of-care devices 148 2000
6489133 Apparatus for determinating the concentration of glucose in whole blood 160 2001
6549796 Monitoring analyte concentration using minimally invasive devices 430 2001
6501976 Percutaneous biological fluid sampling and analyte measurement devices and methods 213 2001
6576416 Analyte measurement device and method of use 193 2001
6491870 Optically readable strip for analyte detection having on-strip orientation index 154 2001
6689411 Solution striping system 168 2001
6676995 Solution striping system 193 2002
6572822 Visual blood glucose test strip 159 2002
 
MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (6)
4897173 Biosensor and method for making the same 533 1987
5120420 Biosensor and a process for preparation thereof 772 1989
5266179 Quantitative analysis method and its system using a disposable sensor 821 1991
5192415 Biosensor utilizing enzyme and a method for producing the same 480 1992
5658443 Biosensor and method for producing the same 164 1994
5948289 Laser beam machining method 54 1996
 
MATRIA HEALTHCARE, LLC (1)
5182707 Apparatus for recording reagent test strip data by comparison to color lights on a reference panel 281 1990
 
YASSINZADEH, ZIA (1)
5700695 Sample collection and manipulation method 392 1994
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
FÉINICS AMATECH TEORANTA (1)
9575027 Systems and methods of discriminating between a control sample and a test fluid using capacitance 0 2013
 
ASCENSIA DIABETES CARE HOLDINGS AG (8)
8401873 Health data management device 1 2008
8649997 Systems and methods for predicting ambient temperature in a fluid analyte meter 2 2009
* 2011/0191,059 Systems and Methods for Predicting Ambient Temperature in a Fluid Analyte Meter 22 2009
8617381 System and apparatus for determining temperatures in a fluid analyte system 7 2010
* 2010/0319,436 System and Apparatus for Determining Temperatures in a Fluid Analyte System 16 2010
9189598 Fluid analyte meter 0 2013
9097650 System and apparatus for determining temperatures in a fluid analyte system 0 2013
9664644 System and apparatus for determining temperatures in a fluid analyte system 0 2015
 
ROCHE DIABETES CARE, INC. (4)
* 2007/0264,721 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT USING A NONLINEAR SAMPLE RESPONSE 113 2007
8148164 System and method for determining the concentration of an analyte in a sample fluid 3 2009
8298828 System and method for determining the concentration of an analyte in a sample fluid 2 2012
8586373 System and method for determining the concentration of an analyte in a sample fluid 0 2012
 
CILAG GMBH INTERNATIONAL (5)
8551320 System and method for measuring an analyte in a sample 5 2009
8932445 Systems and methods for improved stability of electrochemical sensors 0 2010
8617370 Systems and methods of discriminating between a control sample and a test fluid using capacitance 0 2010
9575026 Systems and methods of discriminating between a control sample and a test fluid using capacitance 0 2013
9347910 Systems and methods for improved stability of electrochemical sensors 0 2015
 
LIFESCAN SCOTLAND LIMITED (3)
9638656 Accurate analyte measurements for electrochemical test strip based on multiple discrete measurements defined by sensed physical characteristic(s) of the sample containing the analyte 0 2012
9459231 Method and system to determine erroneous measurement signals during a test measurement sequence 0 2013
9243276 Method and system to determine hematocrit-insensitive glucose values in a fluid sample 9 2013
 
DEXCOM, INC. (6)
9801575 Advanced analyte sensor calibration and error detection 0 2012
9149220 Advanced analyte sensor calibration and error detection 3 2012
9451908 Analyte sensor 1 2012
9700253 Systems and methods for processing analyte sensor data 0 2013
9433376 Systems and methods for processing analyte sensor data 0 2013
9808190 Advanced analyte sensor calibration and error detection 0 2013
 
ROCHE OPERATIONS LTD. (5)
* 7981363 System and method for analyte measurement 14 2008
* 2008/0098,802 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT 123 2008
* 2011/0236,963 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT 0 2011
* 8691152 System and method for analyte measurement 0 2012
* 2012/0135,508 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT 17 2012
 
LIFESCAN, INC. (21)
8529751 Systems and methods for discriminating control solution from a physiological sample 0 2006
* 2007/0235,347 Systems and Methods for Discriminating Control Solution from a Physiological Sample 131 2006
8778168 Systems and methods of discriminating control solution from a physiological sample 2 2008
* 2009/0084,687 SYSTEMS AND METHODS OF DISCRIMINATING CONTROL SOLUTION FROM A PHYSIOLOGICAL SAMPLE 135 2008
8603768 System and method for measuring an analyte in a sample 0 2009
8486649 System and method for measuring an analyte in a sample 0 2009
8877034 Systems, devices, and methods for measuring whole blood hematocrit based on initial fill velocity 0 2009
8101065 Systems, devices, and methods for improving accuracy of biosensors using fill time 8 2009
* 2011/0155,585 Systems, Devices, and Methods for Improving Accuracy of Biosensors Using Fill Time 11 2009
* 2011/0155,584 Systems, Devices, and Methods for Measuring Whole Blood Hematocrit Based on Initial Fill Velocity 9 2009
8449740 Systems and methods for discriminating control solution from a physiological sample 0 2010
* 2011/0011,752 SYSTEMS AND METHODS FOR DISCRIMINATING CONTORL SOLUTION FROM A PHYSIOLOGICAL SAMPLE 14 2010
8623198 Systems, devices, and methods for improving accuracy of biosensors using fill time 3 2010
9157110 Systems and methods of discriminating control solution from a physiological sample 0 2012
9784707 System and method for measuring an analyte in a sample 0 2012
9739745 System and method for measuring an analyte in a sample 0 2012
8916040 System and method for measuring an analyte in a sample 0 2012
8709739 System and method for measuring an analyte in a sample 0 2012
9274078 Systems and methods of discriminating control solution from a physiological sample 0 2013
9404888 Systems, devices and methods for improving accuracy of biosensors using fill time 0 2013
9739749 System and method for measuring an analyte in a sample 0 2014
* Cited By Examiner

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
11.5 Year Payment $7400.00 $3700.00 $1850.00 Dec 24, 2019
Fee Large entity fee small entity fee micro entity fee
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00