US Patent No: 7,390,667

Number of patents in Portfolio can not be more than 2000

System and method for analyte measurement using AC phase angle measurements

ALSO PUBLISHED AS: 20040157337

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Abstract

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A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ROCHE OPERATIONS LTD.HAMILTON60

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beaty, Terry A Indianapolis, IN 46 974
Burke, David W Carmel, IN 77 2281
Kuhn, Lance S Fishers, IN 32 1320
Svetnik, Vladimir Morristown, NJ 24 1545

Cited Art Landscape

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5,288,636 Enzyme electrode system 496 1990
5,508,171 Assay method with enzyme electrode system 459 1994
 
GENERAL ELECTRIC COMPANY (1)
4,865,873 Electroless deposition employing laser-patterned masking layer 68 1987
 
MOLECULAR DEVICES CORPORATION (2)
4,849,330 Photoresponsive redox detection and discrimination 77 1985
4,956,275 Migratory detection immunoassay 105 1987
 
Miles Laboratories, Inc. (1)
4,714,874 Test strip identification and instrument calibration 188 1985
 
The BOC Group, Inc. (1)
4,407,290 Blood constituent measuring device and method 307 1981
 
ROCHE DIAGNOSTICS OPERATIONS, INC. (35)
4,731,726 Patient-operated glucose monitor and diabetes management system 989 1986
4,797,256 Registration device for blood test strips 82 1987
5,053,199 Electronically readable information carrier 154 1989
5,128,015 Method and apparatus for amperometric diagnostic analysis 288 1989
4,963,814 Regulated bifurcated power supply 57 1989
4,999,582 Biosensor electrode excitation circuit 195 1989
4,999,632 Analog to digital conversion with noise reduction 78 1989
5,243,516 Biosensing instrument and method 145 1989
5,232,668 Test strip holding and reading mechanism for a meter 127 1991
5,246,858 Apparatus and method for analyzing a body fluid 72 1991
5,108,564 Method and apparatus for amperometric diagnostic analysis 431 1991
5,371,687 Glucose test data acquisition and management system 450 1992
5,284,770 Meter verification method and apparatus 39 1993
5,385,846 Biosensor and method for hematocrit determination 160 1993
5,352,351 Biosensing meter with fail/safe procedures to prevent erroneous indications 484 1993
5,405,511 Biosensing meter with ambient temperature estimation method and system 212 1993
5,413,690 Potentiometric biosensor and the method of its use 313 1993
5,526,111 Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control 47 1993
5,379,214 Method for reading the concentration of a medically significant component of a biological fluid from a test strip 82 1993
5,437,999 Electrochemical sensor 628 1994
5,594,906 Zero power receive detector for serial data interface 170 1994
5,438,271 Biosensing meter which detects proper electrode engagement and distinguishes sample and check strips 321 1994
5,686,659 Fluid dose flow and coagulation sensor for medical instrument 60 1995
5,710,622 Fluid dose, flow and coagulation sensor for medical instrument 35 1995
5,762,770 Electrochemical biosensor test strip 312 1995
5,832,921 Analog heater control for medical instrument 37 1995
6,162,639 Embossed test strip system 188 1998
6,413,395 Biosensor apparatus 52 1999
6,627,057 Microsphere containing sensor 47 1999
6,413,213 Subscription based monitoring system and method 58 2000
6,645,359 Biosensor 84 2000
6,540,890 Biosensor 62 2000
6,447,657 Biosensor 75 2000
6,544,474 Device for determination of an analyte in a body fluid using small sample sizes 56 2001
* 7,018,843 Instrument 56 2001
 
ST. JUDE MEDICAL, INC. (1)
4,795,542 Electrochemical concentration detector device 111 1986
 
Moorlodge Ventures Limited (1)
6,660,141 Electrochemical sensor 17 2001
 
RHEONIX, INC. (1)
6,358,752 Liposome-enhanced test device and method 54 1999
 
Ortho Pharmaceutical Corporation (1)
5,179,288 Apparatus and method for measuring a bodily constituent 60 1991
 
SEGARS CALIFORNIA PARTNERS, LP (1)
5,220,920 Electrochemical measurement system having interference reduction circuit 71 1991
 
MICROFAB TECHNOLOGIES, INC. (1)
5,658,802 Method and apparatus for making miniaturized diagnostic arrays 213 1995
 
APEX BIOTECHNOLOGY CORP. (1)
6,491,803 Test strip and biosensor incorporating with nanometer metal particles 69 2001
 
Innovative Biotechnologies, Inc. (1)
6,159,745 Interdigitated electrode arrays for liposome-enhanced immunoassay and test device 50 1999
 
WAVESENSE, INC. (1)
6,136,549 systems and methods for performing magnetic chromatography assays 91 1999
 
SIEMENS HEALTHCARE DIAGNOSTICS INC. (7)
5,477,326 Spectrophotometer arrangement with multi-detector readhead 56 1994
5,569,608 Quantitative detection of analytes on immunochromatographic strips 134 1995
5,691,486 Apparatus and methods for selecting a variable number of test sample aliquots to mix with respective reagents 58 1996
5,719,667 Apparatus for filtering a laser beam in an analytical instrument 81 1996
5,745,308 Methods and apparatus for an optical illuminator assembly and its alignment 90 1996
5,945,341 System for the optical identification of coding on a diagnostic test strip 94 1996
6,316,264 Test strip for the assay of an analyte in a liquid sample 55 1999
 
Silver Lake Corporation (1)
6,287,875 Internally referenced competitive assays 40 2000
 
Keith & Rumph Inventors, Inc. (1)
6,126,609 Apparatus for taking blood samples from a patient 30 1998
 
LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (1)
5,698,083 Chemiresistor urea sensor 81 1995
 
CASE WESTERN RESERVE UNIVERSITY (1)
4,571,292 Apparatus for electrochemical measurements 433 1982
 
OPTISCAN, INC. (1)
5,515,847 Self-emission noninvasive infrared spectrophotometer 161 1994
 
QBC DIAGNOSTICS, INC. (4)
5,635,362 Assay of blood or other biologic samples for target analytes 53 1994
5,834,217 Assay of blood or other biologic samples for target analytes 54 1996
5,759,794 Assay of blood or other biologic samples for target analytes 45 1996
5,776,710 Assay of blood or other biologic samples for target analytes 52 1996
 
LIFESCAN, INC. (62)
4,935,346 Minimum procedure system for the determination of analytes 270 1986
5,049,487 Automated initiation of timing of reflectance readings 443 1988
5,059,394 Analytical device for the automated determination of analytes in fluids 362 1988
5,179,005 Minimum procedure system for the determination of analytes 238 1988
5,306,623 Visual blood glucose concentration test strip 238 1991
5,187,100 Dispersion to limit penetration of aqueous solutions into a membrane 202 1991
5,418,142 Glucose test strip for whole blood 213 1992
5,304,468 Reagent test strip and apparatus for determination of blood glucose 621 1993
5,426,032 No-wipe whole blood glucose test strip 301 1993
5,453,360 Oxidative coupling dye for spectrophotometric quantitive analysis of analytes 153 1994
5,515,170 Analyte detection device having a serpentine passageway for indicator strips 178 1994
5,526,120 Test strip with an asymmetrical end insuring correct insertion for measuring 371 1994
5,563,031 Highly stable oxidative coupling dye for spectrophotometric determination of analytes 160 1994
6,335,203 Optically readable strip for analyte detection having on-strip orientation index 149 1994
5,563,042 Whole blood glucose test strip 237 1995
6,395,227 Test strip for measuring analyte concentration over a broad range of sample volume 127 1995
5,620,863 Blood glucose strip having reduced side reactions 161 1995
5,922,530 Stable coupling dye for photometric determination of analytes 121 1995
5,605,837 Control solution for a blood glucose monitor 170 1996
5,780,304 Method and apparatus for analyte detection having on-strip standard 188 1996
5,843,691 Visually-readable reagent test strip 174 1996
6,168,957 Diagnostic test strip having on-strip calibration 169 1997
5,789,255 Blood glucose strip having reduced sensitivity to hematocrit 156 1997
5,843,692 Automatic initiation of a time interval for measuring glucose concentration in a sample of whole blood 191 1997
5,968,760 Temperature-Independent Blood Glucose Measurement 150 1997
6,284,125 Electrochemical cell 191 1998
6,045,567 Lancing device causing reduced pain 213 1999
6,197,040 Lancing device having a releasable connector 180 1999
6,179,979 Electrochemical cell 138 1999
6,200,773 Diagnostics based on tetrazolium compounds 139 1999
6,174,420 Electrochemical cell 133 1999
6,268,162 Reflectance measurement of analyte concentration with automatic initiation of timing 188 1999
6,193,873 Sample detection to initiate timing of an electrochemical assay 306 1999
6,521,182 Fluidic device for medical diagnostics 150 1999
6,261,519 Medical diagnostic device with enough-sample indicator 166 1999
6,379,513 Sensor connection means 66 1999
6,454,921 Electrochemical cell 47 1999
6,218,571 8-(anilino)-1-naphthalenesulfonate analogs 111 1999
6,475,372 Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations 242 2000
6,485,923 Reagent test strip for analyte determination having hemolyzing agent 130 2000
6,325,917 Method and apparatus for automatic analysis 44 2000
6,571,651 Method of preventing short sampling of a capillary or wicking fill device 165 2000
6,488,827 Capillary flow control in a medical diagnostic device 139 2000
6,592,744 Method of filling an amperometric cell 111 2000
6,444,115 Electrochemical method for measuring chemical reaction rates 180 2000
6,632,349 Hemoglobin sensor 190 2000
6,638,415 Antioxidant sensor 135 2000
6,413,410 Electrochemical cell 217 2000
6,475,360 Heated electrochemical cell 177 2000
6,555,061 Multi-layer reagent test strip 180 2000
6,521,110 Electrochemical cell 197 2000
6,531,322 Visual blood glucose test strip 130 2000
6,558,528 Electrochemical test strip cards that include an integral dessicant 181 2000
6,512,986 Method for automated exception-based quality control compliance for point-of-care devices 117 2000
6,489,133 Apparatus for determinating the concentration of glucose in whole blood 131 2001
6,549,796 Monitoring analyte concentration using minimally invasive devices 330 2001
6,501,976 Percutaneous biological fluid sampling and analyte measurement devices and methods 169 2001
6,576,416 Analyte measurement device and method of use 164 2001
6,491,870 Optically readable strip for analyte detection having on-strip orientation index 124 2001
6,689,411 Solution striping system 137 2001
6,676,995 Solution striping system 152 2002
6,572,822 Visual blood glucose test strip 125 2002
 
MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (6)
4,897,173 Biosensor and method for making the same 453 1987
5,120,420 Biosensor and a process for preparation thereof 651 1989
5,266,179 Quantitative analysis method and its system using a disposable sensor 689 1991
5,192,415 Biosensor utilizing enzyme and a method for producing the same 418 1992
5,658,443 Biosensor and method for producing the same 151 1994
5,948,289 Laser beam machining method 50 1996
 
MATRIA HEALTHCARE, LLC (1)
5,182,707 Apparatus for recording reagent test strip data by comparison to color lights on a reference panel 240 1990
 
YASSINZADEH, ZIA (1)
5,700,695 Sample collection and manipulation method 336 1994
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
CILAG GMBH INTERNATIONAL (3)
8,551,320 System and method for measuring an analyte in a sample 0 2009
8,932,445 Systems and methods for improved stability of electrochemical sensors 0 2010
8,617,370 Systems and methods of discriminating between a control sample and a test fluid using capacitance 0 2010
 
ROCHE DIAGNOSTICS OPERATIONS, INC. (3)
8,148,164 System and method for determining the concentration of an analyte in a sample fluid 0 2009
8,298,828 System and method for determining the concentration of an analyte in a sample fluid 2 2012
8,586,373 System and method for determining the concentration of an analyte in a sample fluid 0 2012
 
ROCHE OPERATIONS LTD. (3)
* 7,981,363 System and method for analyte measurement 9 2008
* 8,691,152 System and method for analyte measurement 0 2012
* 2012/0135,508 SYSTEM AND METHOD FOR ANALYTE MEASUREMENT 6 2012
 
BAYER HEALTHCARE LLC (3)
8,401,873 Health data management device 1 2008
8,649,997 Systems and methods for predicting ambient temperature in a fluid analyte meter 1 2009
8,617,381 System and apparatus for determining temperatures in a fluid analyte system 1 2010
 
LIFESCAN, INC. (10)
8,529,751 Systems and methods for discriminating control solution from a physiological sample 0 2006
8,778,168 Systems and methods of discriminating control solution from a physiological sample 0 2008
8,603,768 System and method for measuring an analyte in a sample 0 2009
8,486,649 System and method for measuring an analyte in a sample 0 2009
8,877,034 Systems, devices, and methods for measuring whole blood hematocrit based on initial fill velocity 0 2009
8,101,065 Systems, devices, and methods for improving accuracy of biosensors using fill time 4 2009
8,449,740 Systems and methods for discriminating control solution from a physiological sample 0 2010
8,623,198 Systems, devices, and methods for improving accuracy of biosensors using fill time 2 2010
8,916,040 System and method for measuring an analyte in a sample 0 2012
8,709,739 System and method for measuring an analyte in a sample 0 2012
* Cited By Examiner

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