Real-time impedance assay to follow the invasive activities of metastatic cells in culture
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United States of America Patent
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Jul 15, 2008
Grant Date -
Jun 16, 2005
app pub date -
Sep 10, 2004
filing date -
Sep 10, 2003
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Abstract
The present invention provides methods for the assessment of the metastatic potential of cells by measuring the effect of the cells on the impedance of an electrode. Accordingly, the present invention similarly provides methods for establishing indicators of metastatic potential based on a cell's effect on impedance. Such methods may be employed in vitro or in vivo. In some embodiments, the electrode is coated with endothelial or epithelial cells.
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