Antisense composition and method for treating cancer
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United States of America Patent
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Jul 22, 2008
Grant Date -
Nov 24, 2005
app pub date -
Mar 10, 2005
filing date -
Mar 12, 2004
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method and composition for treating colorectal cancer is disclosed. The method involves administering to a subject, a therapeutically effective amount of a morpholino antisense compound (i) having a nuclease-resistant backbone, (ii) capable of uptake by target cancer cells in the subject, (iii) containing between 10-40 nucleotide bases, and (iv) having a base sequence effective to hybridize to a region of processed or preprocessed human SNAIL RNA transcript.
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