Tissue ablation by shear force for sampling biological fluids and delivering active agents
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United States of America Patent
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Jul 29, 2008
Grant Date -
May 16, 2002
app pub date -
Apr 30, 2001
filing date -
May 1, 2000
priority date (Note) -
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Abstract
The present invention relates to a method and a device for transporting a molecule through a mammalian barrier membrane of at least one layer of cells comprising the steps of: ablating said membrane with a shear device; and utilizing a driving force to move said molecule through said perforated membrane.
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