Reducing cellular dysfunction caused by mitochondrial gene mutations
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Jul 29, 2008
Grant Date -
Jul 22, 2004
app pub date -
Oct 17, 2003
filing date -
Oct 18, 2002
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A synthetic, nuclear-encoded ND4 gene was linked to a mitochondrial targeting sequence and a FLAG epitope tag. This fusion construct was inserted into a rAAV vector. The ND4 fusion protein was expressed and imported into the mitochondria of cells harboring a mitochondrial DNA mutation (G11778A), where it restored cellular respiration.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Advertisement
Advertisement
Advertisement
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully