Multiplexed diagnostic and therapeutics
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United States of America Patent
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Aug 19, 2008
Grant Date -
Feb 5, 2004
app pub date -
Dec 11, 2002
filing date -
Dec 31, 1996
priority date (Note) -
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status (Latency Note)
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Abstract
A method and apparatus for analyzing molecular structures within a sample substance using an array having a plurality of test sites upon which the sample substance is applied. The invention is also directed to a method and apparatus for constructing molecular arrays having a plurality of test sites. The invention allows for definitive high throughput analysis of multiple analytes in complex mixtures of sample substances. A combinatorial analysis process is described that results in the creation of an array of integrated chemical devices. These devices operate in parallel, each unit providing specific sets of data that, when taken as a whole, give a complete answer for a defined experiment. This approach is uniquely capable of rapidly providing a high density of information from limited amounts of sample in a cost-effective manner.
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