Modulation of diacylglycerol acyltransferase 1 expression

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United States of America Patent

PATENT NO 7414033
APP PUB NO 20040209838A1
SERIAL NO

10803482

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Abstract

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Compounds, compositions and methods are provided for modulating the expression of diacylglycerol acyltransferase 1. The compositions comprise oligonucleotides, targeted to nucleic acid encoding diacylglycerol acyltransferase 1. Methods of using these compounds for modulation of diacylglycerol acyltransferase 1 expression and for diagnosis and treatment of disease associated with expression of diacylglycerol acyltransferase 1, such as obesity and obesity-related conditions, are provided.

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Patent Owner(s)

Patent OwnerAddress
ISIS PHARMACEUTICALS INC1896 RUTHERFORD ROAD CARLSBAD CA 92008

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Graham, Mark J San Clemente, CA 123 2420
Monia, Brett P Encinitas, CA 303 5836

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