Length determination of nucleic acid repeat sequences by discontinuous primer extension

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United States of America Patent

PATENT NO 7414115
APP PUB NO 20070178519A1
SERIAL NO

11731192

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Abstract

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Disclosed is a kit useful for determining the number of repeat units in a repeat region of a target nucleic acid comprising: a plurality of different-sequence primers, each containing (i) a target binding segment and (ii) a tag segment having a nucleotide sequence that uniquely identifies the target binding segment, a first primer extension reagent; and a second primer extension reagent, wherein at least one of the first or second primer extension reagents includes an extendible nucleotide having a photodestructible label attached thereto.

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Patent Owner(s)

  • APPLIED BIOSYSTEMS, LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blasband, Andrew J Redwood, CA 10 130
Livak, Kenneth J San Jose, CA 78 3075
Lowe, Adam L San Francisco, CA 7 107

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