Labelled nucleotides
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United States of America Patent
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Aug 19, 2008
Grant Date -
Jul 20, 2006
app pub date -
Aug 22, 2003
filing date -
Aug 23, 2002
priority date (Note) -
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Abstract
The invention provides a nucleotide or nucleoside having a base attached to a detectable label via a cleavable linker, characterised in that the cleavable linker contains a moiety selected from the group comprising: Formula (I) wherein X is selected from the group comprising O, S, NH and NQ wherein Q is a C.sub.1-10 substituted or unsubstituted alkyl group, Y is selected from the group comprising O, S, NH and N(allyl), T is hydrogen or a C.sub.1-10 substituted or unsubstituted alkyl group and * indicates where the moiety is connected to the remainder of the nucleotide or nucleoside).
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