Compositions and methods of using galectin-8 as an inhibitor of tumor cell growth

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United States of America Patent

PATENT NO 7416725
APP PUB NO 20070160602A1
SERIAL NO

11612910

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Abstract

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The present invention provides compositions that enhance or inhibit the interactions of galectin-8 and galectin-8-like proteins with other extracellular matrix proteins or cell surface receptors, and methods for the use thereof as physiological modulators of cell adhesion and in treatment of tumors, both in vivo or ex vivo. It further provides compositions and methods for modulating the expression of galectin-8, and galectin-8-like proteins, particularly to novel antisense oligonucleotides.

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Patent Owner(s)

Patent OwnerAddress
YEDA RESEARCH AND DEVELOPMENT CO LTDTHE WEIZMANN INSTITUTE OF SCIENCE P O BOX 95 REHOVOT 7610002

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arbel-Goren, Rinat Rehovot, IL 2 1
Hadari, Yaron R Rehovot, IL 20 70
Levy, Yifat Rehovot, IL 2 1
Ronen, Denise Rehovot, IL 3 1
Zick, Yehiel Rehovot, IL 5 5

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