Expression of human milk proteins in transgenic plants

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United States of America Patent

PATENT NO 7417178
APP PUB NO 20040111766A1
SERIAL NO

10639835

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Abstract

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The invention is directed to seed and seed extract compositions containing levels of a human milk protein between 3-40% or higher of the total protein weight of the soluble protein extractable from the seed. Also disclosed is a method of producing the seed with high levels of extractable human milk protein. The method includes transforming a monocotyledonous plant with a chimeric gene having a protein-coding sequence encoding a protein normally present in human milk under the control of a seed maturation-specific promoter. The method may further includes a leader DNA sequence encoding a monocot seed-specific transit sequence capable to target a linked milk protein to a storage body.

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Patent Owner(s)

Patent OwnerAddress
INVITRIA INC2718 INDUSTRIAL DRIVE JUNCTION CITY KS 66441

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hagie, Frank E Sacramento, CA 12 310
Huang, Ning Davis, CA 91 770
Rodriguez, Raymond L Davis, CA 23 440

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