Method of making metallopeptides
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United States of America Patent
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Sep 16, 2008
Grant Date -
Jan 5, 2006
app pub date -
Sep 7, 2005
filing date -
Dec 14, 1998
priority date (Note) -
Expired
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Abstract
Method of making metallopeptides is provided, for use in biological, pharmaceutical and related applications. The metallopeptides are made of peptides, peptidomimetics and peptide-like constructs, and include a metal ion-binding region thereof which includes at least one orthogonal sulfur-protecting group, in which the peptide, peptidomimetic or construct is conformationally fixed on deprotection of the sulfur and complexation of the metal ion-binding region with a metal ion while the peptide, peptidomimetic or construct is cleavably bound to solid phase.
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