2,4-Pyrimidinediamine compounds and their uses
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United States of America Patent
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Oct 14, 2008
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app pub date -
Dec 8, 2005
filing date -
Feb 1, 2002
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Abstract
The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades.
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