2-thia-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
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United States of America Patent
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Oct 14, 2008
Grant Date -
Aug 18, 2005
app pub date -
Apr 9, 2003
filing date -
Apr 10, 2002
priority date (Note) -
Expired
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Abstract
The present invention relates to compounds of 2-thia-dibenzoazulene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of tumour necrosis factor-.alpha.(TNF-.alpha.) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action.
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