Compositions for treating abnormalities in glomerular filtration, patent ductus arteriosus and osteoporosis
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United States of America Patent
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Oct 28, 2008
Grant Date -
Jan 23, 2003
app pub date -
Jun 4, 2002
filing date -
Dec 6, 1999
priority date (Note) -
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Abstract
The present invention relates to a composition of matter comprising novel prostaglandin E2 receptor antagonists, and their use in treatments for regulating the fluid filtration in the kidney, preventing bone mineral loss in osteoporosis and dental disease and additionally, closure of ductus arteriosus (DA) in premature infants or fetal animals. Additionally, the compositions include linear peptides, peptide analogs, and peptidomimetics.
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