Method for increasing clinical specificity when detecting tumors and their precursor stages by simultaneously measuring at least two different molecular markers

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United States of America Patent

PATENT NO 7452727
APP PUB NO 20020123845A1
SERIAL NO

10023501

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Abstract

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The present invention relates to an automatable method for the improved diagnosis of pathologically altered cells by simultaneously staining at least two different molecular markers, which exhibit a change in gene expression which is disease-associated, in a cell or constituent regions of a tissue sample by means of using combinations of antibodies and accrediting signal intensities.

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Patent Owner(s)

Patent OwnerAddress
SIEMENS MEDICAL SOLUTIONS DIAGNOSTICS GMBHKARL-HEINZ-KASKE-STRABE 2 ERLANGEN 91052

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bohmann, Kerstin Krefeld, DE 7 178
Hennig, Guido Cologne, DE 21 168
Schopper, Birge Pulheim, DE 1 23
Wirtz, Ralph Cologne, DE 14 247

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