Use of effectors of glutaminyl and glutamate cyclases
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United States of America Patent
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Dec 9, 2008
Grant Date -
Aug 24, 2006
app pub date -
Oct 15, 2004
filing date -
Oct 15, 2003
priority date (Note) -
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Abstract
The present invention provides novel physiological substrates of mammalian glutaminyl cyclase (QC, EC 2.3.2.5), new effectors of QC and the use of such effectors and pharmaceutical compositions comprising such effectors for the treatment of diseases that can be treated by modulation of QC-activity, e.g. diseases selected from the group consisting of duodenal cancer with or w/o Heliobacter pylori infections, colorectal cancer, Zolliger-Ellison syndrome, Familial British Dementia and Familial Danish Dementia.
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