Determination of nucleic acid using electrocatalytic intercalators
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United States of America Patent
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Dec 9, 2008
Grant Date -
Mar 2, 2006
app pub date -
Sep 2, 2004
filing date -
Sep 2, 2004
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Expired
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Abstract
Compositions and methods for electrochemical detection of nucleic acid are disclosed. The compositions comprise electrocatalytic intercalators that bind to double-stranded nucleic acid and oxidize nucleic acid. Methods of detecting nucleic acid in a sample comprise forming double-stranded nucleic acid that is bound by electrocatalytic intercalators wherein the intercalators catalyze oxidation of the nucleic acid at the surface of an electrode.
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