Polymorphism detection and separation
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United States of America Patent
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Dec 23, 2008
Grant Date -
Sep 25, 2003
app pub date -
Sep 27, 2002
filing date -
Sep 27, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Methods and compositions for polymorphism detection and separation. The methods are readily multiplexed, can be adapted to a variety of existing detection systems, and permit target amplification without PCR. The methods permit allelic variants selectively to be isolated, with or without contemporaneous detection, and finds particular utility in facilitating the construction of coisogenic cell collections in which the cells differ genotypically by single nucleotide changes targeted to defined loci.
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