Sterile pharmaceutical composition and process for a solution of propofol emulsion having microbial growth retardation
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United States of America Patent
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Dec 23, 2008
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N/A
app pub date -
Mar 11, 2003
filing date -
Mar 11, 2003
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Abstract
An oil-in-water propofol emulsion that contains soybean oil and egg lecithin, which provide a source of nutrition for microorganisms. Current products include additives to act as a microbial growth retardation agent, the processes described herein detail several methods for the optimization of the innate microbial retardation capability of propofol. Using this process improves the safety of a propofol emulsion solution by controlling microbial growth without the side effects associated with growth retardation additives.
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