Delivery of diazepam through an inhalation route
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United States of America Patent
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-
Dec 30, 2008
Grant Date -
Nov 30, 2006
app pub date -
Aug 7, 2006
filing date -
Nov 9, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to the delivery of compounds for the treatment of anxiety disorders and symptoms of such disorders through an inhalation route. Specifically, it relates to aerosols containing diazepam that are used in inhalation therapy. In a method aspect of the present invention, diazepam is administered to a patient through an inhalation route. The method comprises: a) heating a thin layer of diazepam on a solid support to form a vapor; and, b) passing air through the heated vapor to produce aerosol particles having less than 5% drug degradation products. In a kit aspect of the present invention, a kit for delivering diazepam through an inhalation route is provided which comprises: a) a thin coating of a diazepam composition; and, b) a device for dispending said thin coating as a condensation aerosol.
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