Chimeric empty viral-like particles derived from the infectious bursal disease virus (IBDV), process for their production and applications
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United States of America Patent
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Jan 13, 2009
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May 11, 2006
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Jul 15, 2005
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Abstract
The chimeric empty viral-like particles derived from the infectious bursal disease virus (IBDV) are formed by the assembly of fusion proteins comprising a region A consisting of an IBDV pVP2 protein or a “1-n” fragment of said IBDV pVP2, wherein “n” is an integer comprised between 441 and 501, bound to a region B consisting of a heterologous polypeptide comprising a polypeptide of interest, such as a polypeptide useful for prophylactic, therapeutic or diagnostic purposes.
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