Compounds and methods for modulating functions of nonclassical cadherins

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7476509
APP PUB NO 20040175361A1
SERIAL NO

10714564

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Abstract

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Modulating agents and methods for enhancing or inhibiting nonclassical cadherin-mediated functions, such as atypical or desmosomal cadherin-mediated functions, are provided. The modulating agents comprise at least a tryptophan-containing cell adhesion recognition sequence of an atypical and/or desmosomal cadherin, a conservative analogue or peptidomimetic thereof, or an antibody or fragment thereof that specifically binds to such a cell adhesion recognition sequence. Modulating agents may additionally comprise one or more cell adhesion recognition sequences recognized by cadherins and/or other adhesion molecules. Such modulating agents may, but need not, be linked to a targeting agent, pharmaceutically active substance and/or support material.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ADHEREX TECHNOLOGIES, INC.OTTAWA0

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blaschuk, Orest W Westmount , CA 68 490
Michaud, Stephanie D Hull , CA 5 34

Cited Art Landscape

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Other [Check patent profile for assignment information] (2)
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BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (1)
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