Indole-type derivatives as inhibitors of p38 kinase
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United States of America Patent
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Feb 10, 2009
Grant Date -
Oct 4, 2007
app pub date -
May 22, 2007
filing date -
Sep 3, 2002
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Abstract
The invention is directed to methods to inhibit p38-α kinase using compounds comprising a phenyl or thienyl coupled through a piperidine or piperazine nucleus to an indole residue wherein the indole residue mandatorily has a substituent on the ring nitrogen which is an amino or substituted amino group.
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