Device for chemical and biochemical reactions using photo-generated reagents
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United States of America Patent
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Feb 17, 2009
Grant Date -
Jul 24, 2003
app pub date -
Sep 11, 2002
filing date -
Feb 11, 1998
priority date (Note) -
Expired
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Abstract
This invention provides method and apparatus for performing chemical and biochemical reactions in solution using in situ generated photo-products as reagent or co-reagent. In some embodiments, the present invention provides methods and devices for generating one or more selected multimers at specific reaction sites on a substrate comprising contacting the substrate with a liquid solution comprising photo-reagent precursors, isolating the reaction sites, selectively irradiating the reaction sites with a digital micromirror device, and contacting the substrate with monomers. The method and apparatus of the present invention have applications in parallel synthesis of molecular sequence arrays on solid surfaces.
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