Gene encoding a DNA repair enzyme and methods of use thereof
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United States of America Patent
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Feb 17, 2009
Grant Date -
Apr 17, 2008
app pub date -
Apr 24, 2007
filing date -
Jul 28, 1997
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Abstract
An isolated nucleic acid molecule encoding a human DNA repair enzyme, MED1, is disclosed. Like other mismatch repair genes which are mutated in certain cancers, MED1, encoding nucleic acids, proteins and antibodies thereto may be used to advantage in genetic or cancer screening assays. MED1, which recognizes and cleaves DNA, may also be used for the diagnostic detection of mutations and genetic variants.
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