Drug conjugate composition

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United States of America Patent

PATENT NO 7501120
APP PUB NO 20070009541A1
SERIAL NO

11521129

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides a liquid composition and a lyophilized composition comprising a therapeutically effective amount of a conjugate comprising an antibody chemically coupled to a maytansinoid. The invention further provides a method for killing a cell in a human comprising administering to the human either of the compositions such that the antibody binds to the surface of the cell and the cytotoxicity of the maytansinoid is activated, whereby the cell is killed.

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Patent Owner(s)

  • IMMUNOGEN, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Amphlett, Godfrey Cambridge, US 13 356
Fleming, Michael Londonderry, US 46 1243
Zhang, Wei Cambridge , US 2319 17796

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