Compounds with sulphonamide group and pharmaceutical compositions containing these compounds
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Mar 24, 2009
Grant Date -
Jan 22, 2004
app pub date -
May 8, 2001
filing date -
May 31, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention relates to compounds which, acting as a prodrug and/or support, enable an active agent to be taken up by the erythrocytes and/or an active agent to bind to the erythrocytes. The uptake of these compounds by and/or the binding thereof to the erythrocytes is made possible by a group of formula —SO2NR1R2, wherein R1 and R2, independently of each other, mean a hydrogen atom, an acyl group, an alkyl group, a cycloalkyl group, an aryl group, a cyano group or a hydroxy group. The inventive prodrugs enable active agents such as endogenic substances, natural substances and synthetic substances with therapeutically useful properties which have a high “first path” effect, to be administered orally effectively or significantly improve the oral activity thereof.
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