Methods and reagents for immunization which generate a CD8 T cell immune response
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United States of America Patent
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Apr 7, 2009
Grant Date -
Sep 9, 2004
app pub date -
Apr 28, 2004
filing date -
Jun 9, 1997
priority date (Note) -
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Abstract
New methods and reagents for vaccination are described which generate a CD8 T cell immune response against malarial and other antigens such as viral and tumor antigens. Novel vaccination regimes are described which employ a priming composition and a boosting composition, the boosting composition comprising a non-replicating or replication-impaired pox virus vector carrying at least one CD8 T cell epitope which is also present in the priming composition.
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