Methods for identifying modulators of cyclic nucleotide-gated cation channels
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United States of America Patent
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Apr 7, 2009
Grant Date -
Jun 19, 2008
app pub date -
Apr 17, 2007
filing date -
Aug 17, 2000
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Expired
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Abstract
The invention provides isolated nucleic acid and amino acid sequences of CNG2B, antibodies to CNG2B, methods of detecting CNG2B, and methods of screening for modulators of cyclic nucleotide-gated ion channels using biologically active CNG2B. The invention further provides, in a computer system, a method of screening for mutations of human CNG2B genes as well as a method for identifying a three-dimensional structure of human CNG2B polypeptides.
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