Assay for screening antipsychotic drugs
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United States of America Patent
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Apr 28, 2009
Grant Date -
Nov 9, 2006
app pub date -
Apr 17, 2006
filing date -
Oct 17, 2003
priority date (Note) -
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Abstract
A novel assay method suitable for screening of novel antipsychotics wherein the drugs may be selected based on the differential internalization of the 5-HT2A receptor in neuronal and non-neuronal cell lines effect for it to predict the extrapyramidal symptoms that may be induced by an antipsychotic without having to carry out in vivo experiments.
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