Immunostimulatory nucleic acid molecules

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United States of America Patent

PATENT NO 7524828
APP PUB NO 20050101557A1
SERIAL NO

10921086

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Abstract

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Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful a synthetic adjuvant.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF IOWA RESEARCH FOUNDATION THEOAKDATE RESEARCH CAMPUS 106 TECHNOLOGY INNOVATION CENTER IOWA CITY IA 52242

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kline, Joel N Iowa City, US 11 744
Krieg, Arthur M Wellesley, US 154 11149

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