Modulation of survivin expression
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United States of America Patent
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Jun 2, 2009
Grant Date -
Jul 12, 2007
app pub date -
Jun 3, 2004
filing date -
Jun 3, 2003
priority date (Note) -
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Abstract
Compounds and compositions are provided for modulating the expression of survivin. The compounds, exemplified by those acting through an RNAi antisense mechanism of action, include double-stranded and single-stranded constructs, as well as siRNAs, canonical siRNAs, blunt-ended siRNAs and single-stranded antisense RNA compounds. Methods of using these compounds for modulation of survivin expression and for treatment of diseases associated with expression of survivin are provided.
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