Morphogen-induced nerve regeneration and repair

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United States of America Patent

PATENT NO 7557078
SERIAL NO

08937756

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Abstract

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Disclosed are therapeutic treatment methods, compositions and devices for maintaining neural pathways in a mammal, including enhancing survival of neurons at risk of dying, inducing cellular repair of damaged neurons and neural pathways, and stimulating neurons to maintain their differentiated phenotype. In one embodiment, the invention provides means for stimulating CAM expression in neurons. The invention also provides means for evaluating the status of nerve tissue, including means for detecting and monitoring neuropathies in a mammal. The methods, devices and compositions include a morphogen or morphogen-stimulating agent provided to the mammal in a therapeutically effective concentration.

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Patent Owner(s)

Patent OwnerAddress
STRYKER CORPORATION1941 STRYKER WAY PORTAGE MI 49002

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cohen, Charles M Medway , US 55 943
Kuberasampath, Thangavel Medway , US 76 2499
Oppermann, Hermann Medway , US 112 3953
Ozkaynak, Engin Milford , US 58 1403
Pang, Roy H L Etna , US 50 1132
Rueger, David C Hopkinton , US 109 3184

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