Drug-eluting intravascular prostheses and methods of use
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United States of America Patent
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Jul 21, 2009
Grant Date -
Dec 7, 2006
app pub date -
Jan 31, 2006
filing date -
Jul 20, 2000
priority date (Note) -
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Abstract
The present invention provides intravascular prostheses and methods of production and use. An implantable device for treating a vascular disease or disorder includes an intravascular prosthesis containing an inhibitor of smooth muscle cell proliferation and a growth factor. The device can be coated with a biodegradable drug-eluting polymer that is impregnated with the inhibitor of smooth muscle cell proliferation and the growth factor. The device is useful for treating or preventing a vascular disease or disorder such as restenosis, by simultaneously inhibiting vessel blockage and enhancing recovery of the vessel wall following an intravascular intervention.
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