Amine-linked pyridyl and phenyl substituted piperazine-piperidines with CXCR3 antagonist activity

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7566718
APP PUB NO 20060276480A1
SERIAL NO

11354328

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present application discloses a compound, or enantiomers, stereoisomers, rotamers, tautomers, racemates or prodrug of said compound, or pharmaceutically acceptable salts, solvates or esters of said compound, or of said prodrug, said compound having the general structure shown in Formula 1:and the pharmaceutically acceptable salts, solvates and esters thereof. Also disclosed is a method of treating chemokine mediated diseases, such as, palliative therapy, curative therapy, prophylactic therapy of certain diseases and conditions such as inflammatory diseases (non-limiting example(s) include, psoriasis), autoimmune diseases (non-limiting example(s) include, rheumatoid arthritis, multiple sclerosis), graft rejection (non-limiting example(s) include, allograft rejection, xenograft rejection), infectious diseases (e.g, tuberculoid leprosy), fixed drug eruptions, cutaneous delayed-type hypersensitivity responses, ophthalmic inflammation, type I diabetes, viral meningitis and tumors using a compound of Formula 1.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
MERCK SHARP & DOHME LLC126 EAST LINCOLN AVENUE RAHWAY NJ 07065

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hobbs, Douglas W Yardley, US 24 499
Kozlowski, Joseph A Princeton, US 108 1669
McGuinness, Brian F Plainsboro, US 28 465
Rosenblum, Stuart B West Orange, US 61 1093
Shao, Yuefei Princeton, US 15 433
Shu, Youheng Blue Bell, US 12 175
Wong, Michael K C North Brunswick, US 22 397
Yu, Wensheng Edison, US 66 748

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation