Anionic or cationic dendrimer antimicrobial or antiparasitic compositions
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United States of America Patent
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Aug 11, 2009
Issued Date -
N/A
app pub date -
Aug 26, 2002
filing date -
Sep 14, 1998
priority date (Note) -
Expired
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Abstract
To inhibit, prophylactically or therapeutically, a bacterial, yeast, fungal, or parasitic agent in a patient, an effective amount of a dendrimer is administered to the patient, which dendrimer has a plurality of terminal groups, at least one of which has an anionic- or cationic-moiety covalently bonded or linked thereto. The anionic-containing moiety is not a disaccharide or oligosaccharide moiety, and, where the anionic-containing moiety is a neuraminic- or sialic acid-containing moiety, it is modified in the 4-position by substitution with an amino, amido, cyano, azido or guanido group, or is unsaturated.
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