Methods of assaying receptor activity and constructs useful in such methods

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United States of America Patent

PATENT NO 7572888
APP PUB NO 20040209308A1
SERIAL NO

10785841

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Abstract

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Described are methods of detecting G-protein coupled receptor (GPCR) activity in vivo and in vitro; methods of assaying GPCR activity; and methods of screening for GPCR ligands, G protein-coupled receptor kinase (GRK) activity, and compounds that interact with components of the GPCR regulatory process. Constructs useful in such methods are described.

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Patent Owner(s)

  • DUKE UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barak, Lawrence S Durham, US 22 301
Caron, Marc G Hillsborough, US 53 562
Ferguson, Stephen S London, CA 6 196
Zhang, Jie Wallingford, US 950 8108

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