IL-1 antagonist formulations
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United States of America Patent
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Aug 11, 2009
Grant Date -
Jan 17, 2008
app pub date -
May 18, 2007
filing date -
Aug 17, 2004
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Abstract
Formulations of an interleukin-1 (IL-1) antagonist are provided including a pre-lyophilized formulation, a reconstituted lyophilized formulation, and a stable liquid formulation. Preferably, the IL-1 antagonist is an IL-1 trap composed of a dimer of two fusion protein having an amino acid sequence selected from the group consisting of SEQ ID NO: 10.
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