Indirubin derivatives having anticancer property against human cancer cell line
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United States of America Patent
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Aug 11, 2009
Grant Date -
Jul 5, 2007
app pub date -
Jan 26, 2005
filing date -
Jan 27, 2004
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Abstract
The present invention relates to an indirubin derivative having anticancer property by inhibiting cell proliferation as to human cancer cell line. More particularly, this invention provides the synthesis of indirubin derivative known as CDK(Cyclin-dependent kinase) inhibitor. Further, inhibition activity of proliferation as to human cancer cell line and apoptosis against induced-differentiation of said indirubin derivative are researched to develop a novel indirubin derivative having efficacious anticancer properties as to various human cell lines.
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