Nucleic acids encoding neutralizing GDF8 epitope-based peptides and fusion proteins
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United States of America Patent
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Sep 8, 2009
Grant Date -
Sep 18, 2008
app pub date -
Apr 2, 2008
filing date -
Dec 31, 2003
priority date (Note) -
Expired
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Abstract
The invention provides new, specific nucleic acids encoding antigenic peptides from the protein GDF8. The invention also provides nucleic acids encoding fusion proteins comprising the new peptides, immunogens and vaccines based on the nucleic acids encoding new peptides and/or fusion proteins, antibodies that specifically bind to the new peptides of GDF8, and methods of treating animals in order to modulate the activity of GDF8, employing vaccines or antibodies according to the invention.
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