Metering doses of sample liquids
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United States of America Patent
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Sep 22, 2009
Grant Date -
Aug 18, 2005
app pub date -
Aug 5, 2004
filing date -
Feb 17, 2004
priority date (Note) -
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status (Latency Note)
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Abstract
A method of metering and mixing a dose of a sample liquid with a diluent liquid includes introducing a sample liquid into a channel defined in a housing. The housing defines a pocket open to the channel and sized to both collect a metered dose of the sample liquid, and to retain the collected dose by capillary force when the channel is emptied. The sample liquid is then removed from the channel under conditions that enable retention of the collected, metered dose of the sample liquid in the pocket. Following a cleaning step, a volume of diluent liquid is introduced into the channel to induce diffusion and mixing of the diluent liquid with the dose of sample liquid to form a mixture.
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