Use of prion conversion modulating agents

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United States of America Patent

PATENT NO 7598046
APP PUB NO 20070020682A1
SERIAL NO

10560978

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The use of Apolipoprotein B, Apolipoprotein E, fragments and mimetics thereof is provided for diagnostic, detection, prognostic and therapeutic applications In prion diseases. More specifically, the invention provides the use of Apolipoprotein B or fragments thereof for modulating or identifying modulators of the prion protein replication which are implicated in the pathogenesis of transmissible spongiform encephalopathics and other prion diseases.

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Patent Owner(s)

  • MERCK SERONO SA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Maundrell, Kinsey Geneva , CH 6 17
Soto-Jara, Claudio Friendswood , US 21 129

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