PUFA polyketide synthase systems and uses thereof
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United States of America Patent
Stats
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Oct 27, 2009
Grant Date -
Feb 21, 2008
app pub date -
Jul 16, 2007
filing date -
Jan 14, 1999
priority date (Note) -
In Force
status (Latency Note)
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Forward Citations
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Abstract
The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.

First Claim
Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | Total Patents |
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DSM IP ASSETS B.V. | 6411 TE HEERLEN | 1309 |
International Classification(s)

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- [Patents Count]
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
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Barclay, William R | Boulder , US | 102 | 3459 |
Flatt, James H | Colorado Springs , US | 48 | 1816 |
Metz, James G | Longmont , US | 80 | 2766 |
Weaver, Craig A | Boulder , US | 49 | 1680 |
Cited Art Landscape
Patent Info | (Count) | # Cites | Year |
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5310242 Portable infant seat | 60 | 1992 | |
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2005/0164,192 Transgenic plants expressing enzymes involved in fatty acid biosynthesis | 140 | 2005 | |
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2004/0172,682 Production of very long chain polyunsaturated fatty acids in oilseed plants | 80 | 2004 | |
7125672 Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts | 74 | 2004 | |
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2002/0138,874 Elongase genes and uses thereof | 51 | 2001 | |
2005/0014,231 Genes involved in polyketide synthase pathways and uses thereof | 31 | 2003 | |
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2008/0038,378 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 39 | 2007 | |
2008/0038,379 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 48 | 2007 | |
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5672491 Recombinant production of novel polyketides | 213 | 1994 | |
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6033883 Production of polyketides in bacteria and yeast | 83 | 1997 | |
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6503706 Method for identifying human and animal cells having an unlimited proliferation of tumor-formation potential | 51 | 1996 | |
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2008/0044,870 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
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2005/0089,865 Delta 6 desaturases from primulaceae, expressing plants and pufa-containing oils | 73 | 2004 | |
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2004/0005,672 Heterologous production of polyketides | 55 | 2003 | |
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5639790 Plant medium-chain thioesterases | 114 | 1993 | |
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5130242 Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids | 291 | 1990 | |
5908622 Food product containing thraustochytrium and/or schizochytrium microflora and an additional agricultural based ingredient | 89 | 1997 | |
6566583 Schizochytrium PKS genes | 93 | 1999 | |
7001772 Product and process for transformation of Thraustochytriales microorganisms | 90 | 2002 | |
7214853 Schizochytrium PKS genes | 65 | 2002 | |
7211418 PUFA polyketide synthase systems and uses thereof | 76 | 2004 | |
7217856 PUFA polyketide synthase systems and uses thereof | 73 | 2004 | |
7256022 Pufa polyketide synthase systems and uses thereof | 50 | 2005 | |
7256023 PUFA polyketide synthase systems and uses thereof | 52 | 2005 | |
7259295 PUFA polyketide synthase systems and uses thereof | 50 | 2005 | |
7271315 PUFA polyketide synthase systems and uses thereof | 72 | 2006 | |
2007/0256,146 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 46 | 2007 | |
2007/0244,192 PLANT SEED OILS CONTAINING POLYUNSATURATED FATTY ACIDS | 75 | 2007 | |
2007/0270,494 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS | 72 | 2007 | |
2008/0026,434 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
2008/0026,435 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
2008/0026,438 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 36 | 2007 | |
2008/0026,439 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 37 | 2007 | |
2008/0026,440 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 38 | 2007 | |
2008/0032,351 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 38 | 2007 | |
2008/0038,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 36 | 2007 | |
2008/0022,422 CHIMERIC PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 69 | 2007 | |
2008/0148,433 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
2008/0038,791 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 37 | 2007 | |
2008/0038,792 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 36 | 2007 | |
2008/0044,867 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 38 | 2007 | |
2008/0038,793 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
2008/0038,794 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
2008/0038,795 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
2008/0038,796 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
2008/0038,797 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
2008/0040,822 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 50 | 2007 | |
2008/0044,869 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
2008/0044,871 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 45 | 2007 | |
2008/0044,872 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
2008/0044,873 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
2008/0050,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
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5246841 Microbial process for production of eicosapentaenoic acid | 72 | 1991 | |
5683898 Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid | 85 | 1995 | |
5798259 Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid | 73 | 1996 | |
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6140486 Production of polyunsaturated fatty acids by expression of polyketide-like synthesis genes in plants | 110 | 1998 | |
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2007/0245,431 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS | 80 | 2007 | |
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2004/0010,817 Plant acyl-CoA synthetases | 51 | 2003 | |
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2004/0139,498 Fatty acid elongase 3-ketoacyl CoA synthase polypeptides | 48 | 2004 |
Patent Citation Ranking
Forward Cite Landscape
Patent Info | (Count) | # Cites | Year |
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9580758 System and method for the detection and treatment of infection by a microbial agent associated with HIV infection | 0 | 2014 | |
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8940884 Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof | 0 | 2010 | |
* 2010/0266,564 Polyunsaturated Fatty Acid Synthase Nucleic Acid Molecules and Polypeptides, Compositions, and Methods of Making and Uses Thereof | 7 | 2010 | |
8426686 Polyunsaturated fatty acid production in heterologous organisms using PUFA polyketide synthase systems | 1 | 2010 | |
* 2011/0167,508 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 5 | 2010 | |
8309796 Chimeric PUFA polyketide synthase systems and uses thereof | 0 | 2011 | |
8859855 Chimeric PUFA polyketide synthase systems and uses thereof | 0 | 2012 | |
9382521 Polyunsaturated fatty acid production in heterologous organisms using PUFA polyketide synthase systems | 0 | 2013 |
Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
---|---|---|---|---|
11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Apr 27, 2021 |
Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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