US Patent No: 7,608,753

Number of patents in Portfolio can not be more than 2000

PUFA polyketide synthase systems and uses thereof

ALSO PUBLISHED AS: 20080044868

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Abstract

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The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
DSM IP ASSETS B.V.6411 TE HEERLEN1260

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barclay, William R Boulder, CO 160 2551
Flatt, James H Longmont, CO 77 1436
Metz, James G Longmont, CO 137 2134
Weaver, Craig A Boulder, CO 88 1343

Cited Art Landscape

Patent Info (Count) # Cites Year
 
DSM IP ASSETS B.V. (37)
5,130,242 Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids 218 1990
5,908,622 Food product containing thraustochytrium and/or schizochytrium microflora and an additional agricultural based ingredient 69 1997
6,566,583 Schizochytrium PKS genes 66 1999
7,001,772 Product and process for transformation of Thraustochytriales microorganisms 60 2002
7,214,853 Schizochytrium PKS genes 46 2002
7,211,418 PUFA polyketide synthase systems and uses thereof 55 2004
7,217,856 PUFA polyketide synthase systems and uses thereof 54 2004
7,256,022 Pufa polyketide synthase systems and uses thereof 46 2005
7,256,023 PUFA polyketide synthase systems and uses thereof 47 2005
7,259,295 PUFA polyketide synthase systems and uses thereof 46 2005
7,271,315 PUFA polyketide synthase systems and uses thereof 54 2006
2007/0256,146 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2007/0244,192 PLANT SEED OILS CONTAINING POLYUNSATURATED FATTY ACIDS 55 2007
2007/0270,494 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS 52 2007
2008/0026,434 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0026,435 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0026,438 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 35 2007
2008/0026,439 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 35 2007
2008/0026,440 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 36 2007
2008/0032,351 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 36 2007
2008/0038,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 35 2007
2008/0022,422 CHIMERIC PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 52 2007
2008/0148,433 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0038,791 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 35 2007
2008/0038,792 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 35 2007
2008/0044,867 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 36 2007
2008/0038,793 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0038,794 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 41 2007
2008/0038,795 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0038,796 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 41 2007
2008/0038,797 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0040,822 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0044,869 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 41 2007
2008/0044,871 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0044,872 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0044,873 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0050,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 40 2007
 
Sagami Chemical Research Center (3)
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ABBOTT LABORATORIES (2)
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2005/0014,231 Genes involved in polyketide synthase pathways and uses thereof 27 2003
 
E. I. DU PONT DE NEMOURS AND COMPANY (2)
2004/0172,682 Production of very long chain polyunsaturated fatty acids in oilseed plants 56 2004
7,125,672 Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts 63 2004
 
MARTEK BIOSCIENCES CORPORATION (2)
2008/0038,378 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 35 2007
2008/0038,379 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
 
MONSANTO COMPANY (2)
5,639,790 Plant medium-chain thioesterases 94 1993
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BIOTICA TECHNOLOGY LIMITED (1)
6,033,883 Production of polyketides in bacteria and yeast 76 1997
 
IACR-ROTHAMSTED (1)
2005/0089,865 Delta 6 desaturases from primulaceae, expressing plants and pufa-containing oils 55 2004
 
KOSAN BIOSCIENCES, INC. (1)
2004/0005,672 Heterologous production of polyketides 51 2003
 
Miami University, an Ohio corporation (1)
2004/0139,498 Fatty acid elongase 3-ketoacyl CoA synthase polypeptides 44 2004
 
ROCHE DIAGNOSTICS GMBH (1)
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SEMBIOSYS GENETICS INC. (1)
2007/0245,431 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS 55 2007
 
SUPERMEDIA LLC (1)
2008/0044,870 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (1)
5,672,491 Recombinant production of novel polyketides 165 1994
 
THE UNIVERSITY OF YORK (1)
2005/0164,192 Transgenic plants expressing enzymes involved in fatty acid biosynthesis 117 2005
 
WASHINGTON STATE UNIVERSITY (1)
2004/0010,817 Plant acyl-CoA synthetases 44 2003
 
Other [Check patent profile for assignment information] (1)
5,310,242 Portable infant seat 57 1992

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
DSM IP ASSETS B.V. (2)
8,426,686 Polyunsaturated fatty acid production in heterologous organisms using PUFA polyketide synthase systems 0 2010
8,309,796 Chimeric PUFA polyketide synthase systems and uses thereof 0 2011

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