Cyclic natriuretic peptide constructs

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United States of America Patent

PATENT NO 7622440
APP PUB NO 20070265206A1
SERIAL NO

11694260

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Cyclic constructs with an N-terminus and a C-terminus which bind to a natriuretic peptide receptor and include a plurality of amino acid residues, at least one amino acid surrogate of formula I:where R, R′, Q, Y, W, Z, J, x and n are as defined in the specification, and optionally at least one prosthetic group, pharmaceutical compositions including such cyclic constructs, and methods of treating congestive heart failure or other conditions, syndromes or diseases for which induction of anti-hypertensive, cardiovascular, renal or endocrine effects are desired.

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Patent Owner(s)

Patent OwnerAddress
PALATIN TECHNOLOGIES INC4-B CEDAR BROOK DRIVE CRANBURY NJ 08512

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bastos, Margarita Plainsboro , US 14 93
Cai, Hui-Zhi East Brunswick , US 13 53
Sharma, Shubh D Cranbury , US 66 825
Yang, Wei Edison , US 1193 4487

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